Experts tell you the diagnosis of vulvar leukoplakia

Vulvar leukoplakia, also known as chronic vulvar dystrophy, refers to a group of diseases caused by nutritional disorders of the vulvar skin and mucous membranes, resulting in tissue degeneration and pigment changes. The formation of this disease is mostly related to the malnutrition of the nerves and blood vessels in the deep connective tissue of the vulva, which leads to pathological changes in the skin covering it. The following is an introduction to the diagnosis of vulvar leukoplakia.

Clinical features of vulvar leukoplakia: Itching of the vulva, sometimes with burning and pain. The skin of the affected area is rough, thickened with moss-like appearance, with scratches, and sometimes with chapped skin. Local pigmentation is reduced, and the labia majora and labia minora generally turn white. Mild atrophy can be seen on the vulva. In severe cases, the clitoris, labia majora and labia minora atrophy and adhesion, and the labia minora partially or completely disappear, and then tighten together, the vaginal opening is narrow and elastic, and even affects urination and sexual life.

In addition to the above-mentioned unique symptoms and signs, the diagnosis of vulvar leukoplakia should be based on pathological diagnosis as the final conclusion. Because a variety of diseases can cause skin itching and loss or depigmentation of pigments, although the manifestations are different, it is difficult to distinguish them with the naked eye. Even if the naked eye can diagnose, it is not possible to do pathological typing, especially to find atypical hyperplasia (precancerous lesions) early. Literature reports that about 50% of vulvar squamous cell carcinomas are often accompanied by vulvar white lesions. Therefore, if the lesions are atypical or there are chronic chapped skin, localized thickening, and ulceration, it is necessary to rely on biopsy for diagnosis.

When taking samples, it is necessary to take samples from multiple points of the lesion: ulcers, chapped skin, nodules, protrusions or rough areas, and take samples appropriately. Method: Apply 1% toluidine blue to the lesion area first, wait for it to dry, and then use 1% acetic acid solution to decolorize it. Use biopsy forceps to perpendicularly hold the skin in the non-decolorized area and take biopsy samples deep into the dermis. Any non-decolorized area indicates that there are naked nuclei in the area, which suggests that biopsy in this area can improve the accuracy of diagnosis.

This is the diagnosis of vulvar leukoplakia. Benign keratotic lesions in the vulva are called white keratosis. White keratosis that does not heal for a long time may further develop into vulvar leukoplakia. The cause is unclear, but it may be related to systemic factors, such as diabetes and endocrine disorders. For more questions, please consult online experts.

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