What medicine should I take for endometrial thickening?

The thickness of the endometrium changes regularly with the onset of menstruation. Some endometrial thickening is a pathological symptom that will affect our health and deserves our attention. What medicine should I take for endometrial thickening?

1: Danazol is a derivative of ethynyl-testosterone and is a commonly used drug for the treatment of endometriosis. It has a strong anti-proliferative effect on the endometrium. Treatment with a dose of 200 mg/d for 3 months has a significant effect on endometrial hyperplasia.

2: Cottonpol is an effective drug used in my country to treat endometrial hyperplastic functional uterine bleeding and endometriosis. Its mechanism of action is to inhibit the ovaries, and it also has a specific inhibitory effect on the endometrium. After treatment, the pathological morphology of the endometrium is highly atrophic, and the ultrastructure has obvious degenerative changes. The initial effect of using cottonpol to treat endometrial atypical hyperplasia has been observed in Peking Union Medical College Hospital. There was one case of atypical hyperplasia, and the endometrial atypical hyperplasia improved after using shujing phenol, but it still recurred. After 8 months of treatment with cottonpol, the endometrium atrophied, and soon after, the woman became pregnant and gave birth to a boy.

The thickness of the endometrium changes regularly with the onset of menstruation, but some endometrial thickening is a pathological symptom that will affect our health and deserves our attention. Endometrial thickening is mainly due to the secretion of estrogen, which strengthens the blood supply to the endometrium. So what effects does endometrial thickening have on women? Let's take a look!

Causes of endometrial thickening

The thickness of the endometrium changes regularly with the onset of menstruation, but some endometrial thickening is a pathological symptom that can affect our health and deserves our attention.

The blood supply to the endometrium is enhanced, and the phenomenon of gradual thickening, i.e. proliferative endometrium, occurs. The cause of endometrial thickening is mostly related to excessive ovarian estrogen secretion and progesterone deficiency. If the ovarian hormones are disordered, a large amount of estrogen will stimulate the endometrium, which can easily lead to abnormal endometrial thickening and endometrial thickening.

During the ovarian cycle, when the follicles in the ovaries develop and mature, they will secrete estrogen and take effect, which will strengthen the blood supply to the endometrium and cause the endometrium to thicken, providing good conditions for the implantation of the fertilized egg and the growth and development of the embryo. After ovulation, under the action of the progesterone and estrogen secreted by the corpus luteum of the ovary, the thickened endometrium will secrete, which is the secretory endometrium.

Excessive estrogen and insufficient progesterone may be due to taking contraceptives without progesterone or using hormone replacement without progesterone. The chance of this happening is higher in patients with chronic anovulation, such as polycystic ovary disease, late menopause, or obese women who have menopause.