Progesterone , also known as progesterone, is a progestogen that is often used to artificially adjust the menstrual cycle in clinical practice . However, progesterone is not a panacea . Progesterone is a natural progestogen secreted by the corpus luteum of the ovary . It has a significant morphological effect on the endometrium stimulated by estrogen in the body and is necessary for maintaining pregnancy . Its pharmacological effects are mainly : ① In the late menstrual cycle, the glands in the uterine mucosa grow , the uterus becomes congested , and the endometrium thickens , preparing for the implantation of the fertilized egg . After the fertilized egg is implanted , the placenta is produced, and the excitability of the pregnant uterus is reduced , its activity is inhibited , and the fetus grows safely . ②Under the combined action of estrogen , it promotes full breast development and prepares for milk production . ③ It closes the cervix , reduces and thickens the mucus , and makes it difficult for sperm to penetrate ; in large doses, it inhibits the secretion of pituitary gonadotropin through negative feedback on the hypothalamus , thus inhibiting ovulation . ④ Competitively antagonizes aldosterone , promotes the excretion of sodium ions and chloride ions and promotes diuresis . ⑤It has a mild effect of increasing body temperature , making the basal body temperature higher during the luteal phase of the menstrual cycle . When women find themselves suffering from amenorrhea symptoms , they must go to the hospital for examination and receive targeted treatment in time . Do not take progesterone blindly to avoid side effects of drugs due to improper use , which may harm your health . |
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