Causes and hazards of hydatidiform mole

Causes and hazards of hydatidiform mole

The main causes of hydatidiform mole include genetic factors, environmental influences and physiological abnormalities. It will also cause harm to the patient's reproductive system and overall health. In very serious cases, it may even develop into invasive hydatidiform mole or choriocarcinoma.

From the cause point of view, the main cause of hydatidiform mole is chromosomal abnormalities during embryonic development. Normally, a complete hydatidiform mole is formed by diploid chromosomes from the father, while the mother's genetic material is missing, while a partial hydatidiform mole is mostly caused by the presence of triploid chromosomes in the fertilized egg. Environmental factors such as malnutrition (especially vitamin A deficiency), advanced pregnancy, or a previous history of hydatidiform mole can also increase the probability of disease. Personal physiological factors such as abnormal egg quality and immune system disorders may also lead to the occurrence of hydatidiform mole. After the onset of the disease, hydatidiform mole may manifest as symptoms such as vaginal bleeding, abnormal enlargement of the uterus, and hyperemesis gravidarum. Its harm cannot be ignored, especially invasive hydatidiform mole and transformation into malignant tumors, which will directly threaten life safety.

From the cause point of view, the main cause of hydatidiform mole is chromosomal abnormalities during embryonic development. Normally, a complete hydatidiform mole is formed by diploid chromosomes from the father, while the mother's genetic material is missing, while a partial hydatidiform mole is mostly caused by the presence of triploid chromosomes in the fertilized egg. Environmental factors such as malnutrition (especially vitamin A deficiency), advanced pregnancy, or a previous history of hydatidiform mole can also increase the probability of disease. Personal physiological factors such as abnormal egg quality and immune system disorders may also lead to the occurrence of hydatidiform mole. After the onset of the disease, hydatidiform mole may manifest as symptoms such as vaginal bleeding, abnormal enlargement of the uterus, and hyperemesis gravidarum. Its harm cannot be ignored, especially invasive hydatidiform mole and transformation into malignant tumors, which will directly threaten life safety.

In order to reduce the risk of hydatidiform mole and its deterioration, pregnant women should undergo regular ultrasound examinations in early pregnancy to detect lesions in time. In terms of treatment, the most common method is to remove the lesion by suction uterine extraction, and laparotomy can also be selected according to the specific situation. If necessary, drugs such as methotrexate can help control more serious malignant lesions. Serum HCG levels should be monitored regularly after surgery to ensure that there are no residual lesions and to prevent recurrence in time. At the same time, pregnancy should be avoided for at least 1-2 years to avoid increasing the probability of recurrence.

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