What are the causes of recurrent miscarriage? There are 6 major reasons

There are many reasons for recurrent miscarriage, and they are complicated. Genetic factors are one of them. In addition, if the uterine anatomy is abnormal, it can also cause recurrent miscarriage. In addition, if the expectant mother is infected with a virus during pregnancy, has endocrine abnormalities, or suffers from a disease that increases the risk of thromboembolic disease, it can cause recurrent miscarriage. Finally, abnormalities in the immune system can also easily cause miscarriage.

Recurrent miscarriage refers to spontaneous miscarriage that occurs 2 or more times in a row. Among most spontaneous miscarriages during pregnancy, "embryo arrest" is a more common type. Recurrent miscarriage can cause great harm to the mother physically and mentally, so it is very important to understand the causes and take preventive measures. Let's take a look at the causes of recurrent miscarriage.
1. Genetic factors <br/>Mainly refers to abnormalities in the number or structure of chromosomes, which is the most common cause of miscarriage, accounting for about 50% of miscarriages.
2. Anatomical factors <br/>Abnormal uterine anatomy can lead to about 15%-20% of miscarriages. Common uterine anatomy abnormalities mainly include uterine septate, endometrial polyps, submucous myoma, uterine adhesions, cervical dysfunction, etc. Uterine septate is the most common uterine malformation associated with recurrent miscarriage.
3. Infection factors <br/>During pregnancy, systemic infection or local infection of the reproductive and urinary system may lead to miscarriage. When excluding the cause of recurrent miscarriage, examination of genital chlamydia, mycoplasma, and secretions is very necessary.
4. Endocrine factors <br/>Common endocrine abnormalities associated with recurrent spontaneous abortion include luteal insufficiency, thyroid dysfunction, hyperprolactinemia, insulin resistance, hyperandrogenism, etc. Patients with excessive obesity, emaciation, and irregular menstruation should pay special attention to the screening of related endocrine abnormalities.
5. Thrombophilia refers to a class of diseases that increase the risk of thromboembolic diseases. Due to the special changes in the blood system during pregnancy, a hypercoagulable state is caused, which increases the possibility of thrombosis, which occurs in the tiny blood vessels of the placenta and may lead to embryo arrest, pregnancy-induced hypertension, placental abruption, fetal growth restriction, etc.
6. Immune factors <br/>The human immune system is like its own defense system. It will automatically eliminate foreign invaders. Half of the embryo comes from the father and will be rejected by the immune system. However, in a normal immune system, there is an immune tolerance mechanism that allows the embryo to grow healthily in the mother's body. If the immune system is overactive, the ability to reject foreign substances will be enhanced, and the embryo will be rejected, leading to spontaneous abortion.