There are several ways to check for hyperprolactinemia.

The purpose of analyzing the examination methods of hyperprolactinemia is to help everyone actively diagnose this disease, and then help everyone actively treat it. So what are the examination methods for hyperprolactinemia? The following are professional answers given by experts, let us give professional answers.

Hyperprolactinemia test method:

1. Sella CT scan: In normal women, the anterior-posterior diameter of the sella turcica is <17mm, the depth is <13mm, the area is <130mm2, and the volume is <1100mm3. CT scan should be performed if the following images are present:

①Expanded like a sailboat;

②Double saddle bottom or heavy edge;

③High/low density area or inhomogeneity within the saddle;

④ Deformation of the plate;

⑤ Calcification foci on the sella turcica; ⑥ Osteoporosis of the anterior and posterior clinoid processes;

⑦ Intrasellar cavitation;

⑧Bone destruction.

2. Magnetic resonance imaging (MRI), cavernous sinus angiography, pneumoencephalography, and cerebral angiography can determine the location and size of the tumor and help differentiate it from other intracranial lesions. Since the false positive and false negative rates of CT diagnosis are 20% and the accuracy rate is only 61%, MRI is recommended for diagnosis.

3. Serum PRL determination and PRL dynamic test:

In non-prolactinoma-induced hyperPRLemia, PRL rarely exceeds 200ng/ml. Those with >200ng/ml are very likely to have PRL tumors. The larger the PRL tumor, the higher the PRL level, which may even exceed 2000ng/ml. Mild PRL increase (<60ng/ml) may be due to stress or pulse secretion peak. To avoid stress, blood can be collected for 3 consecutive days or 3 consecutive blood collections on the same day, each separated by 1 hour. In this way, the pulse peak can be excluded from the 3 serum measurement values, which is conducive to the judgment of high PRL secretion. Drugs that stimulate PRL secretion, such as TRH, metoclopramide, chlorpromazine, cimetidine, or drugs that inhibit PRL secretion, such as levodopa, can be selectively used to observe the dynamic changes of PRL. PRL tumors have no obvious changes or weakened reactions to the above stimulants and inhibitors, which can be used to distinguish idiopathic hyperPRLemia from RPL tumors, but when the PRL level is high, its identification value is small.

The above-mentioned hyperprolactinemia examination method is more common in professional hospitals. After mastering the hyperprolactinemia examination method, everyone is required to go to a professional hospital to treat this disease in order to restore everyone's health to the greatest extent.