Can menopause be completely cured? Many people are troubled by this question. During the menopausal transition period, functional uterine bleeding may lead to endometrial cancer. Therefore, the principle of treatment for functional uterine bleeding during this period is to stop bleeding, reduce menstruation, or promote amenorrhea to prevent endometrial cancer. Let me introduce it below. 1. Drug treatment of functional uterine bleeding during the menopausal transition period. In principle, the lowest effective hormone dose should be used for patients with less bleeding to reduce the side effects of the drug, so as to achieve the purpose of hemostasis; for patients with more bleeding, it is required that the effect of sex hormones is seen within 8 hours of application, and the bleeding basically stops within 24 to 48 hours. If the bleeding continues for more than 96 hours, the diagnosis of functional uterine bleeding should be reconsidered. In recent years, with the development of contraceptives, the emergence of third-generation contraceptives, which contain highly selective progestins, can be used to treat functional uterine bleeding during the menopausal transition period. In addition, mifepristone is a progesterone antagonist at the receptor level, which can reduce menstrual volume and promote amenorrhea. In clinical treatment, the most appropriate means should be selected according to individual differences, and targeted treatment should be given. 2. Endometrial shedding method: Patients with functional uterine bleeding during the menopausal transition period are affected by the lack of progesterone in the endometrium. A sufficient amount of progesterone is given to convert the endometrium into the secretory phase, and then the progesterone is discontinued. After the drug is discontinued, the endometrium is exfoliated and bleeding occurs, and the purpose of hemostasis is achieved, which is also called drug-induced curettage. Progesterone is often injected intramuscularly. Medroxyprogesterone tablets can also be used. Fukang tablets. Because the withdrawal bleeding after discontinuation of the drug is large, it is not suitable for patients with severe anemia. It is only suitable for patients with mild anemia and long-term bleeding. 3. The principle of endometrial atrophy hemostasis is that a large dose of synthetic progesterone inhibits the secretion of gonadotropin by the pituitary gland through negative feedback, thereby inhibiting the secretion of estrogen by the ovaries, causing the endometrium to atrophy and achieve the purpose of hemostasis. Fukang Tablets, Angong Progesterone, gradually reduce the dosage after the bleeding stops and continue to use the medicine for about 21 days. It is suitable for women with severe anemia and heavy menstrual flow. |
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