Long-term use of drugs can cause irregular menstruation

Menstruation is an external manifestation of the maturity of the female reproductive endocrine system. Usually, female neuroendocrine system is affected by many factors, including thyroid and adrenal dysfunction, tension, anxiety, overwork, etc. In fact, the use of some drugs can also cause irregular menstruation.

Antipyretic analgesic

Long-term use of painkillers such as ibuprofen can lead to menstrual disorders, and it is worth noting that once such menstrual disorders occur, it is not easy to return to normal. Therefore, it is best for women not to take painkillers on their own for a long time. If pain occurs, it is best to find out the cause before receiving treatment.

Gastrokinetic drugs

Some women who take domperidone (trade name "Motilium") due to poor digestive function will have elevated serum prolactin (PRL) levels, causing infrequent menstruation, galactorrhea, amenorrhea and other reactions. Generally speaking, the condition will return to normal after stopping the medication. If you need to take it frequently, you should regularly test the serum prolactin level. If it is greater than 100 micrograms/liter, you should stop taking the medication immediately and consult a doctor for follow-up treatment plans.

Antifungal drugs, antiallergic drugs, and hormones

Ketoconazole is used for skin and nail tinea, vaginal candidiasis, and can bring forward menstruation and significantly increase menstrual blood volume. The anti-allergic drug astemizole (trade name "Astemizole") can bring forward menstruation. Adrenal cortex hormone drugs such as cortisone and hydrocortisone, long-term and large-scale use can cause central obesity, menstrual disorders, etc. The menstrual disorders caused by these two types of drugs can disappear on their own after stopping the medication, so if you take the medicine according to the doctor's instructions, you generally don't need to be too nervous.