Symptoms and pathological features can be used to diagnose vulvar leukoplakia

The symptoms of the disease are one of the bases for diagnosing vulvar leukoplakia. A detailed understanding of its manifestations is very effective in diagnosing vulvar leukoplakia. So, how to diagnose vulvar leukoplakia? Let's ask the experts to tell us in detail how to diagnose vulvar leukoplakia .

Vulvar pruritus is the first prominent symptom felt by patients, especially at night. The degree of itching is related to time, menstruation, climate, food, environment, and mood. Itching usually occurs intermittently, and patients often scratch because of the itching. Due to scratching, there are many scratches and redness and swelling in the vulva. As a result of long-term itching, local ulceration, chapped skin, ulceration and secondary infection occur. Therefore, whether the patient has itching symptoms can be used to diagnose vulvar leukoplakia.

Vulva itching, sometimes with burning and pain. The skin of the affected area is rough, thickened like moss, with scratches, and sometimes cracks. Local pigmentation is reduced, and the labia majora and labia minora generally turn white. Mild atrophy can be seen on the vulva. In severe cases, the clitoris, labia majora and labia minora atrophy and adhesion, and the labia minora partially or completely disappears, and then tightens, the vaginal opening is narrow, and elasticity disappears, and even urination and sexual life are affected.

In addition to the above symptoms for diagnosing vulvar leukoplakia, pathological diagnosis should be the final conclusion. Because a variety of diseases can cause skin itching and loss of pigment or decolorization, although the manifestations are different, it is not easy to distinguish them with the naked eye. Even if the naked eye can diagnose, it is not possible to do pathological typing, especially to find atypical hyperplasia (precancerous lesions) early. It has been reported that about 50% of vulvar squamous cell carcinomas are often associated with vulvar white lesions. Therefore, if the lesions are atypical or there are chronic chapped, localized thickening, and ulceration, it is necessary to rely on biopsy pathological examination for diagnosis. When taking samples, it is necessary to take samples from multiple points such as ulcers, chapped, nodules, protrusions or rough areas, and the samples should be taken appropriately. Method: 1% toluidine blue can be applied to the lesion area first, and then 1% acetic acid solution can be used for decolorization after it dries. In the non-decolorized area, biopsy forceps are used to be perpendicular to the skin and deep into the dermis for biopsy. Any area that does not discolor indicates the presence of naked nuclei, suggesting that biopsy in this area can improve the accuracy of diagnosis.

The above is the introduction of "diagnosis of vulvar leukoplakia", for reference only. The diagnosis of vulvar leukoplakia mainly starts from its symptoms and pathological characteristics, and comprehensive consideration can effectively diagnose vulvar leukoplakia. If you still have doubts about the diagnosis of vulvar leukoplakia, you can consult a gynecologist online.