Causes of hydatidiform mole

The occurrence of hydatidiform mole may be related to genetic factors, environmental influences, physiological abnormalities, maternal trauma and pathological diseases. The cause should be identified early and professional treatment should be sought.

1. Genetic factors

The occurrence of hydatidiform mole is closely related to genetic abnormalities. Some cases are caused by chromosomal abnormalities during fertilization, especially paternal chromosomal abnormalities. For example, complete hydatidiform mole is common in cases where the genetic material in the egg is missing, but the genetic material of the fertilized sperm is abnormally replicated. Partial hydatidiform mole may be related to the presence of triploid chromosomes in the fertilized egg. Genetic screening can effectively understand genetic tendencies, especially women with a family history of genetic diseases should pay special attention.

2 Environmental factors

Harmful substances in the environment may increase the risk of hydatidiform mole, such as long-term exposure to chemical toxins, bad living habits such as smoking, alcoholism or severe radiation. These external factors may affect the normal development of eggs or embryos. It is recommended to avoid exposure to harmful substances before pregnancy and maintain a healthy lifestyle.

3 Physiological abnormalities

The physiological characteristics of the mother may also lead to the formation of hydatidiform mole, such as abnormal ovarian function and abnormal uterine morphology. Women who are pregnant at an advanced age, especially those over 35 years old and those with a history of multiple miscarriages, have a relatively high risk of developing hydatidiform mole. It is recommended that women of childbearing age have regular physical examinations, especially a detailed gynecological examination before pregnancy.

4 Traumatic factors

Repeated uterine surgeries, a history of miscarriage, or pelvic infection may damage the uterine environment, affect the normal implantation and development of the embryo, and thus lead to the formation of hydatidiform mole. Pay attention to uterine health, avoid unnecessary intrauterine operations, and provide professional care after surgery.

5 Pathological diseases

Mole is closely related to certain diseases, such as endocrine diseases such as thyroid disease, maternal immune system abnormalities or diabetes, which can affect the embryonic development process in early pregnancy. Complete mole may increase the risk of female malignancies such as choriocarcinoma. It is necessary to detect and treat the primary disease as early as possible, and control health indicators before pregnancy.

If hydatidiform mole is suspected, the patient should immediately seek medical attention for ultrasound examination and serum HCG test to confirm the diagnosis, and choose treatment according to the condition, including surgical uterine curettage, chemotherapy and long-term follow-up. Healthy women need to monitor their physical condition regularly, especially during pregnancy, and must follow the doctor's instructions to ensure a safe pregnancy.