Why do patients with recurrent miscarriage need immunological examination?

It is not uncommon for women to have three or more miscarriages. If you do not pay attention to it, you may lose the right to be a mother. In order to better understand the patient's condition, doctors will ask patients with repeated miscarriages to undergo immunological tests. Let me talk about why patients with repeated miscarriages need immunological tests.

Habitual abortion refers to three or more consecutive spontaneous abortions. According to the time of occurrence of habitual abortion, abortion can be divided into early habitual abortion and late abortion. In recent years, recurrent abortion has been used to replace habitual abortion, which is replaced by two or more spontaneous abortions, and each abortion often occurs in the same month of pregnancy. Traditional Chinese medicine calls it "slippery abortion".

The causes of habitual miscarriage are mostly luteal insufficiency, hypothyroidism, congenital uterine malformations, uterine developmental abnormalities, intrauterine adhesions, uterine fibroids, chromosomal abnormalities, autoimmunity, etc.

Generally speaking, women with habitual miscarriages should first rule out non-immune causes before preparing to get pregnant again, because endocrine dysfunction can be adjusted with drugs, certain chromosomal abnormalities that cause miscarriage cannot be solved by current medicine, and problems such as abnormal uterine morphology and intrauterine adhesions must be solved by surgery.

If the above tests are normal, you should consider immune-related factor tests. Clinically, about 80% of habitual miscarriages are related to immune abnormalities. That is, during pregnancy, the woman's body produces an immune response against the man, causing the embryo to be unable to survive in the mother's body, resulting in miscarriage.

The immune etiology classification must be correct in order to choose a more effective treatment plan. It is very important for patients to wait patiently and cooperate with the examination. If the immune examination is started before the body has fully recovered after abortion, the various indicators will not reach a stable state and cannot reflect the real situation.

Quick reading of habitual abortion examination, clinical significance, main examination items, endocrine factors, basal body temperature, blood estrogen, progesterone, prolactin, etc., infectious factors, leucorrhea, Toxoplasma, Mycoplasma, Chlamydia, cytomegalovirus, herpes simplex virus, rubella virus, etc., reproductive factors, hysterosalpingography, hysteroscopy, etc., genetic factors, chromosome karyotype analysis of both spouses, immune factors, zona pellucida antibodies, phospholipid antibodies, ABO blood type antibodies, blocking antibodies, blocking antibodies, anti-idiotypic antibodies, etc.