How to treat premature ovarian failure better

The emergence of premature ovarian failure will make some young female patients enter old age early, and the incidence of premature ovarian failure has been increasing in recent years. Therefore, everyone must understand the treatment methods of premature ovarian failure. If premature ovarian failure unfortunately occurs, what methods can be used to treat it?

The cause of premature ovarian failure is still unclear in most patients. It is believed to be related to genetics, autoimmune processes, infection, etc. Among them, the most research is on premature ovarian failure and autoimmunity. The abnormalities that have been found include antibodies to FSH, antibodies to FSH receptors, antibodies to parathyroid glands, thyroid glands and adrenal glands, etc. Some patients have recovered ovarian function after immunosuppressive treatment.

Tests for autoimmune diseases include blood calcium, phosphorus, fasting blood sugar, morning cortisol, free T4, TSH, thyroid antibodies (such as thyroid dysfunction), complete blood count, erythrocyte sedimentation rate, total protein, albumin/globulin ratio, rheumatoid factor, antinuclear antibodies, etc. Genetic abnormalities are also heterogeneous and multifactorial, including FSH receptor abnormalities, translocation of homologous sequences of X and Y chromosomes, FSH structural abnormalities (inability to bind to receptors), etc. Infectious factors include mumps, viral infections, etc.

Normal women's ovarian function begins to decline at the age of 45 to 50. If there are signs of decline before the age of 40, it is medically called premature ovarian failure. Such women are often accompanied by amenorrhea or oligomenorrhea, increased gonadotropin levels and decreased estrogen levels, and clinical manifestations include varying degrees of hot flashes, sweating, vaginal dryness, decreased libido and other pre- and post-menopausal symptoms.

Premature ovarian failure is one of the important causes of female infertility. Many women with this disease are not optimistic about the treatment of this disease. In fact, there is no need to have this idea, because there are many modern methods to cure premature ovarian failure. The following are some methods to treat premature ovarian failure:

1. Immunotherapy for premature ovarian failure: Immunotherapy is feasible for those who are found to have antibody factors. Immunization vaccination has become a more reliable treatment method.

2. Surgical treatment of premature ovarian failure. For POF caused by ovarian vascular factors leading to ovarian nutrient deficiency, early diagnosis and early treatment should be carried out. Vascular bypass surgery should be performed as soon as possible before the ovarian function is completely lost, such as anastomosis of the ovarian artery with the inferior mesenteric artery or renal artery, to restore the ovarian blood supply and revitalize the ovary. For those who are in the late stage of POF or have ovarian deficiency due to various reasons, ovarian transplantation has become a very successful treatment method. With the help of a small part of another person's ovary, female physiological functions can be completed.

3. In addition to amenorrhea, only a few patients have symptoms similar to menopause, so they are often ignored and do not receive treatment. However, if young women are in a state of low estrogen for a long time, they will experience uterine atrophy, reduced vaginal secretions, sexual pain, and even long-term calcium deficiency leading to osteoporosis. Therefore, estrogen should be supplemented in time. For those who may be able to restore ovarian function and hope to have children, ovulation-inducing drugs can also be added.

Through the detailed introduction of premature ovarian failure in the above article, we have also discovered that premature ovarian failure can lead to female infertility, so we must have a grasp of the treatment methods of premature ovarian failure introduced in the above article. The editor reminds everyone that female friends should develop the good habit of going to the hospital for regular physical examinations.