What causes menopause in women?

Menopause is a necessary stage for every woman. It can be said to be a turning point in the life of female friends. After menopause, various signs of the body begin to age. However, female friends must not be pessimistic about this. This is the normal development of human beings and is inevitable. The early or late menopause time is caused by many factors. The following introduces the causes of menopause:

1. Genetic factors

Impact on postmenopausal women The DNA sequence and its variation in the human body reflect the human evolution process. Studying DNA sequence variation (i.e. polymorphisms) in different populations and individuals helps to understand human physiological changes, the occurrence and development of diseases, and the response to drug treatment.

2. Ovarian aging

(1) Follicle reduction and ovarian morphological aging. At birth, there are about 700,000 to 2 million follicles in the ovaries. There are still about 400,000 follicles during puberty. There may be very few follicles left at menopause. There are two ways to cause follicle reduction: ovulation and atresia.

(2) Decline of ovarian function Women's fertility begins to decline between the ages of 30 and 35, and declines significantly when they are close to 40. From regular menstruation to menopause, there is usually a period of irregular menstruation. During this period, the follicles mature irregularly, ovulation may or may not occur, and the cycle may be normal, long, short, or completely unpredictable. Therefore, the length of the cycle and its changes can also be used to reflect ovarian function.

3. Atrophy of the reproductive tract

Changes: The vulva loses most of its collagen, fat and ability to retain water, glands atrophy, secretion decreases, sebum secretion also decreases, and the skin becomes thinner, dry, and cracked. The vagina shortens, narrows, has fewer wrinkles, thins the wall, weakens elasticity, and secretions decrease. In the early stage, it shows congestive changes, the wall is fragile and easy to be injured and bleed, there are diffuse or scattered ecchymoses, and in the late stage, the color becomes pale and the adhesion bands increase.