Surgical cure rate of cervical precancerous lesions

Clinical follow-up observations show that it takes about 10 years for general cervical precancerous lesions to develop into cervical precancerous lesions. From this perspective, cervical precancerous lesions are not terrible, they are a preventable and curable disease. The key to prevention and treatment is to conduct regular gynecological examinations, detect and treat cervical precancerous lesions in a timely manner, and stop their development into cervical precancerous lesions. If prevention and control measures can be implemented, the cure rate of cervical precancerous lesions is very high.

For a long time, the treatment of patients with cervical precancerous lesions has been based on the treatment model of "radiotherapy as the main method, early surgery, and chemotherapy is useless". This is because radiotherapy for patients with cervical precancerous lesions is not only very effective, but also has no surgical risks and can be used in all stages; while surgical treatment is only suitable for early stage patients; the effect of chemotherapy is even more unsatisfactory.

However, long-term clinical practice has confirmed that radiotherapy alone is not effective for patients with larger cancer lesions. In addition, radiotherapy can damage the ovaries and vagina, causing women to lose their sexual and reproductive abilities. It is necessary to explore new treatment methods, and neoadjuvant chemotherapy came into being at this time.

Neoadjuvant chemotherapy for cervical precancerous lesions refers to chemotherapy before surgery, which can reduce the size and scope of the tumor, reduce the tumor stage, and allow patients who were previously unable to undergo surgery to regain the opportunity for surgery while preserving ovarian function. If the patient's vagina is removed too much, vaginal lengthening surgery can also be performed to improve their quality of life.

Currently, the commonly used chemotherapy regimen is mainly a combination of platinum-based drugs. Therefore, for young and middle-aged patients who still have sexual life or have fertility needs, a new treatment model of "surgery first, preoperative chemotherapy, and preservation of function" can be implemented.

However, the specific treatment plan should be selected according to the clinical stage. For example, extrafascial hysterectomy or sub-radical hysterectomy can be performed in stage Ⅰa; for young patients with cervical precancerous lesions in stage Ⅰa and some stage Ⅰb1 who want to retain fertility, cervical radicular resection plus lymph node dissection can be performed, so that only the cervix is ​​removed while the uterus, fallopian tubes, and ovaries are preserved. In this way, 1/3 of the patients can have children within 1 year, and 2/3 of the patients can enjoy the joy of being a mother within 3 years.

However, if the patient is in a very advanced stage, it is not recommended to use very drastic treatments that will cause great pain to the patient, because at this time the possibility of recovery is very small. Not only can drastic treatments not improve the patient's survival, but they also seriously affect their quality of life. At this time, mild treatment is the basis for the patient's recovery. DD patients live with tumors for a period of time while waiting for the emergence of new treatments. Keep in touch with the doctor frequently, and continue treatment once a new opportunity is found, so as to get the best treatment effect.