Why do patients with uterine fibroids experience heavy bleeding?

Uterine bleeding is a major symptom of uterine fibroids. Its clinical manifestations include excessive menstrual bleeding and prolonged menstruation. The main reasons are as follows.

1. Large endometrial shedding area

Larger or multiple myomas will increase with the increase of the area of ​​the endometrium in the uterine cavity, causing the patient to experience a larger surface of endometrial shedding during menstruation, making the local repair time correspondingly longer, resulting in more uterine bleeding and longer menstrual periods.

2. The uterus cannot contract effectively

Patients with intramural fibroids often have poor uterine contractility, which reduces their ability to control bleeding and causes heavy uterine bleeding.

3. Associated with dysfunctional uterine bleeding

Patients with uterine fibroids who are in the late reproductive age or approaching menopause may experience excessive menstruation even if the fibroids are not large. This may be caused by associated dysfunctional uterine bleeding. The patient needs to undergo a curettage and examination of the endometrium before a diagnosis can be made.

4. Abnormal uterine vascular structure

Basic fibroblast growth factor, vascular endothelial growth factor, epidermal growth factor, etc. produced by uterine fibroids themselves and their muscle wall tissues, or the direct effects of regulatory disorders of their receptors on vascular function and growth, can all cause abnormal structure of uterine blood vessels and lead to more uterine bleeding.