What is the reason for miscarriage when sperm does not liquefy?

Sperm failure to liquefy may lead to fertility difficulties. If a miscarriage occurs after pregnancy, the cause may be sperm quality problems, the female's physical condition, or abnormal development of the fertilized egg. It is necessary to comprehensively analyze the cause, improve the sperm liquefaction state, and receive reasonable treatment under the guidance of a doctor.

1. Genetic factors may lead to sperm liquefaction disorders

Some men may be born with abnormal sperm liquefaction function due to family genetic defects. This is due to defects in certain genes related to prostate secretion and sperm protein decomposition, which leads to insufficient activity of sperm decomposition enzymes and affects the function of sperm in the female reproductive tract. Once a family history of similar fertility disorders is found, genetic testing can be selected for screening, and assisted reproductive technology can be used under the guidance of a doctor to increase the success rate of pregnancy.

2. Environmental factors affect sperm quality

Sperm liquefaction failure may also be related to external environmental factors. For example, long-term exposure to toxic chemicals (such as pesticides, heavy metals, etc.), high temperature environments (such as long-term saunas, high-temperature workplaces), or frequent smoking and drinking can reduce prostate and sperm function. Excessive stress in life or irregular work and rest can also affect endocrine levels, thereby inducing insufficient sperm liquefaction ability. Improving lifestyle is the key, such as quitting smoking and limiting alcohol, avoiding exposure to high temperatures and toxic environments, and ensuring adequate sleep.

3. Male prostate or reproductive system diseases

Male diseases such as prostatitis and seminal vesiculitis may lead to abnormal secretion of prostatic fluid and insufficient proteolytic enzymes in semen, thus affecting the liquefaction process of semen. If accompanied by symptoms of urogenital tract infection (such as urgency, frequency, and pain), timely medical treatment for etiological examination is required. Treatment methods include antibiotic treatment (such as levofloxacin, amoxicillin-clavulanate potassium, etc.) and physical therapy (prostate massage, local physical therapy, etc.).

4. Women’s health status

If a woman has a miscarriage after pregnancy, it may also be due to certain health problems, such as insufficient endometrium, abnormal immune system (such as anti-sperm antibodies or autoimmune diseases), ovarian dysfunction, etc. It is recommended that women go to the hospital for a comprehensive fertility assessment, and if necessary, they can use Chinese medicine conditioning or hormone therapy to improve the function of the reproductive system. For example, women with insufficient corpus luteum function can use progesterone injection or supplement related drugs.

5. Abnormal development of the embryo itself

Even if the sperm successfully liquefies and combines with the egg, chromosomal abnormalities in the embryo may lead to miscarriage. Such problems can be avoided through embryo chromosome testing (such as third-generation IVF technology). For couples with repeated miscarriages, it is recommended to combine the chromosome test reports of both parties to find the root cause, and at the same time, take artificial assisted pregnancy technology in a timely manner according to the doctor's advice.

Improving the situation of sperm liquefaction requires a comprehensive treatment plan. Men should pay attention to health management and treat potential diseases in a timely manner, while women should monitor their physical condition regularly. If miscarriage or difficulty conceiving occurs repeatedly, it is recommended that both husband and wife seek medical treatment together to find the specific cause and receive targeted treatment to create conditions for healthy birth.