Does hydatidiform mole affect life expectancy?

Doctors at the Obstetrics and Gynecology Hospital said that hydatidiform mole is a unique disease associated with pregnancy, known as gestational trophoblastic disease, which manifests as edema and degeneration of the placental villi, forming a series of large and small blisters, generally without normal embryonic tissue. In a few cases, it can coexist with the fetus. So, will hydatidiform mole affect people's life expectancy?

As long as hydatidiform mole is treated in time, it will not affect the patient's life span.

Hydatidiform mole is more common in rice-eating countries, so it is believed to be related to nutrition. Studies have found that patients with gestational trophoblastic tumor (GTT) have low serum folate activity. Folic acid deficiency during the embryonic angiogenesis period affects the synthesis of thymine, leading to embryonic death and lack of placental villous blood vessels; low dietary carotene consumption increases the risk of hydatidiform mole; the incidence of hydatidiform mole increases in areas with vitamin A deficiency; and the content of trace elements Zn and Se in hydatidiform mole tissue decreases.

It is extremely important to follow up hydatidiform mole, which can detect malignant transformation early and use chemotherapy in time. After uterine curettage, hydatidiform mole should be checked for blood and urine HCG once a week, and then once every half month after 3 months, and continue for 1 year, and then once every half year for 2 years. Follow-up should pay special attention to the changes in blood and urine HCG. Gynecological examinations should also be performed to understand the state of uterine involution and pay attention to whether the patient has abnormal vaginal bleeding, hemoptysis and other metastatic symptoms. Pelvic B-ultrasound, chest X-ray or CT examinations should be performed in parallel. Malignant transformation of hydatidiform mole often occurs within one year, but there are also more than 10 years. The follow-up period should be more than 10 to 15 years.