Professional knowledge on causes of miscarriage

The causes of miscarriage are very complicated. Some female friends even experience multiple miscarriages but cannot accurately find the cause. Most experts believe that occasional miscarriages are mostly related to the environment and/or trauma, and repeated miscarriages may be related to immune and genetic factors. Let's take a look at the experts' introduction to the professional knowledge related to the causes of miscarriage.

Causes of miscarriage:

1. Embryonic (or fetal) factors

1. Abnormal embryonic development: It is the most common cause of early miscarriage, and miscarriage caused by chromosomal abnormalities accounts for about 50-60%.

2. Placental abnormalities: Due to incomplete development of the trophoblast, degeneration of the placental villi, or the placenta is attached too low, fetal-placental circulation may be impaired, leading to miscarriage.

2. Maternal factors

1. Acute infectious diseases, which may cause fetal death due to pathogens or toxins invading through the placenta, or cause uterine contractions and miscarriage due to high fever or poisoning;

2. Severe anemia or heart failure, resulting in fetal death due to lack of oxygen;

3. Endocrine disorders, such as corpus luteum insufficiency, lead to decidua dysplasia and affect the development of fertilized eggs;

4. Uterine hypoplasia, uterine fibroids or deformities can also hinder embryonic development;

5. Sometimes, the relaxation of the internal cervix can cause the inability to withstand the increased pressure of the fetal sac, leading to late miscarriage;

6. Strong mental stimulation, trauma or sexual intercourse can also cause miscarriage, but the inducing factors are often mainly caused by defects in the embryo itself.

(III) External factors

Toxic substances that can cause miscarriage include cadmium, lead, organic mercury, DDT and other radioactive substances. These toxic substances may act directly on fetal somatic cells, or they may affect the fetus through the placenta, causing miscarriage.

(IV) Immune factors

After pregnancy, the mother rejects the fetus due to immune incompatibility between the mother and the fetus, resulting in miscarriage. The immune factors that have been discovered include the spouse's tissue compatibility antigens, fetal antigens, blood type antigens, imbalance in maternal cellular immune regulation, maternal blocking antibodies during pregnancy, and lack of maternal cytotoxic antibodies against paternal lymphocytes.

(V) Incompatibility of blood types between mother and child

Incompatibility of blood types between mother and child often causes late miscarriage, such as ABO blood type and Rh blood type incompatibility.

The above is an introduction to the professional knowledge related to the causes of miscarriage. I hope it will be helpful to you.