What causes threatened miscarriage in women

What causes threatened miscarriage in women? Threatened miscarriage does not occur without reason. It may be caused by some unique reasons. Only by understanding the causes of threatened miscarriage can we do a good job of prevention and treatment. So what causes threatened miscarriage in women? Let's learn about this issue together.

Causes of miscarriage

1. Chromosomal abnormalities: Chromosomal abnormalities include abnormal chromosome number, such as monosomy, trisomy, and polyploidy; structural abnormalities, such as breakage, deletion, and translocation can all lead to miscarriage.

Some people have studied chromosomes in spontaneous abortion and therapeutic abortion and found that 60% of spontaneous abortions have abnormal karyotypes. Abnormal karyotypes are often accompanied by structural abnormalities in the fetus or placenta. In contrast, most aborted fetuses with normal karyotypes are normal.

2. Endocrine disorders: Excessive estrogen and insufficient progesterone are also causes of early miscarriage. During the 12th to 14th week of pregnancy, the placenta is formed to replace the function of the corpus luteum, which is prone to endocrine disorders, especially corpus luteum insufficiency.

In addition, the lack of thyroid hormone hinders the cellular oxidation process, and hyperthyroidism and diabetes are prone to miscarriage.

3. Placental abnormalities and placental endocrine insufficiency: Decidualitis during early pregnancy can cause bleeding or hyperplasia of the basal decidua, dissolution of the chorionic epithelial cells and decidual cells, and blockage of blood vessels in the villi, affecting the absorption and transportation of nutrients, resulting in the separation of the fertilized egg from the attachment site, bleeding and miscarriage.

In addition, huge infarction in the placenta can reduce the function of the placenta and affect the survival of the fetus. It is also not uncommon for placenta previa and placental villous edema to lead to miscarriage. After pregnancy, if the levels of beta-hCG, hPL, P, E2, and estrone in the mother's blood decrease in early pregnancy, 50% of miscarriages will occur.

4. Blood type incompatibility: Due to previous pregnancy or blood transfusion, the Rh factor and incompatible ABO blood type factor produce antibodies in the mother. During this pregnancy, the antibodies enter the fetus through the placenta and agglutinate with red blood cells to produce hemolysis, resulting in miscarriage.

5. Psychoneural factors: such as fright, severe mental stimulation, etc. can also cause miscarriage. In recent years, studies have shown that noise and vibration have a certain impact on human reproduction.