What causes congenital absence of vagina?

The gynecological disease congenital absence of vagina is very rare in life, so we don’t know much about this disease. However, if a child in the family has this disease, the parents will be very distressed. So, what exactly causes the child to suffer from congenital absence of vagina? The following is a detailed explanation of this.

What are the causes of congenital absence of vagina?

This disease is caused by internal or external factors hindering the development of the embryo, or it may be caused by abnormal development of the paramesonephric duct due to gene mutation (which may have a family history).

The causes of the disease are generally related to the following phenomena:

1. Chromosome abnormality.

2. Androgen insensitivity syndrome.

3. The mother uses male hormones, anti-cancer drugs, thalidomide, etc. in early pregnancy.

4. Infection with certain viruses or toxoplasma in early pregnancy.

The potential hazards of congenital absence of vagina are:

1. Causes abdominal pain: Congenital absence of vagina may cause menstruation to be retained in the abdominal cavity for a long time and difficult to discharge. Periodic abdominal pain may occur after the menarche. Rectal examination may feel a mass formed by blood accumulation, which will naturally affect women's daily life.

2. With or without uterine developmental abnormalities: If the uterus develops abnormally and manifests as primary amenorrhea after puberty, the uterus will be small or deformed. If the uterus develops normally, primary amenorrhea will occur with cyclical abdominal pain, intrauterine blood, enlarged uterus, and sexual dysfunction.

3. Incomplete development of secondary sexual characteristics: Patients with incomplete ovarian development have incomplete development of secondary sexual characteristics, short stature, webbed neck, cubitus valgus and other deformities, which have a great impact on their lives.

Through reading the above content, we found that most of the causes of congenital absence of vagina are caused by chromosomal abnormalities. Therefore, young couples who plan to get pregnant need to go to the hospital for a pre-pregnancy check-up, which is helpful in preventing congenital absence of vagina.