What are the early diagnosis bases for hyperprolactinemia?

What are the diagnostic bases for hyperprolactinemia in the early stage? This is what everyone is more concerned about. Only by understanding the diagnostic bases for hyperprolactinemia can we make a correct diagnosis and implement active treatment. Next, we will give a detailed interpretation of the diagnostic bases for hyperprolactinemia.

Patients with galactorrhea and hypogonadism should consider the possibility of high PRL, which can be diagnosed by measuring blood PRL. Normal male blood PRL generally does not exceed 0.68nmol/L (15ng/ml), and female blood PRL is generally 0.23-0.91nmol/L (5-20ng/ml). Since PRL is secreted in a pulsatile manner and is affected by many factors, it is best to repeat the measurement. It is worth noting that a small number of people have normal blood PRL in the morning but elevated blood PRL at night. These patients need to measure the nighttime blood PRL level and perform a provocative test. Commonly used provocative tests include the TRH test and the metoclopramide (metoclopramide) test.

The dose of metoclopramide test is 10 mg, which can be taken orally, or injected intravenously or intramuscularly. The PRL peak value appears 60 to 120 minutes after oral administration, and the peak value appears 20 to 60 minutes after intravenous or intramuscular injection. The peak value of normal people is more than 3 times the base value. PRL tumor patients are slow to respond to TRH and metoclopramide, and the multiple increase of PRL after administration is not as high as that of normal people, but the absolute value of the increase is higher than that of normal people.

The above is an analysis of the diagnostic basis of hyperprolactinemia. Experts point out that the diagnostic basis of hyperprolactinemia must be grasped. Only in this way can everyone's safety be guaranteed to the greatest extent. Finally, it is recommended that everyone must actively go to a regular hospital to treat this disease.