Hyperprolactinemia diagnostic process

The occurrence of hyperprolactinemia is closely related to the increase of serum prolactin. The presence of this disease will cause amenorrhea, galactorrhea, infertility and other phenomena. So how should hyperprolactinemia be checked? What is the diagnostic process of hyperprolactinemia?

Women can use the following methods to test for hyperprolactinemia:

1. Interview and physical examination: The interview should include whether the patient is taking medication for peptic ulcer, central nervous system disease, or hypertension and when the medication is taken.

During the initial visit, the breasts must be checked for milk secretion. Chiari-Frommel syndrome patients secrete the most milk, while other patients generally need to be squeezed to secrete milk. Use progesterone to observe whether there is withdrawal bleeding. Most patients with pituitary adenoma have second-degree amenorrhea.

2. Blood prolactin value determination: The disease can only be diagnosed when the blood prolactin value measured by radioimmunoassay exceeds 1nmol/L. The prolactin value is higher in pituitary adenoma.

3. CT or MRI photography of the sella turcica: When the blood prolactin value is above 4nmol/L or accompanied by headache, visual impairment, hemianopsia, etc., patients should be advised to undergo CT or MRI photography of the sella turcica.

4. Potential hyperprolactinemia:

1. Measure the prolactin level in the blood at night, but this is difficult to do in actual work.

2. Perform a TRH test. TRH 500 pg is injected intravenously. The basal prolactin level should be below 1 nmol/L before administration. Blood should be drawn 15 and 30 minutes after administration to measure prolactin. If the level exceeds 5 nmol/L, a diagnosis can be made.

Now everyone has a clear understanding of the examination process of hyperprolactinemia, right? Only by doing the relevant examination work can we clearly diagnose the existence of the disease, and then treat it according to the patient's condition and restore health as soon as possible.