What are the symptoms of hyperprolactinemia?

Hyperprolactinemia is a disease that affects women's fertility plans. Although the incidence is not very high, it is more difficult to treat, so early detection is very important. What are the typical symptoms of hyperprolactinemia? The main manifestations are reduced menstrual volume, galactorrhea, and some people have symptoms of osteoporosis. Everyone must pay attention and check in time if abnormal symptoms occur.

Hyperprolactinemia is the most common pituitary disease, with galactorrhea and hypogonadism as prominent manifestations. Female patients may experience decreased libido and loss of sexual desire, which will be relieved after treatment as PRL levels decrease. So, what are the typical symptoms of hyperprolactinemia?

1. Decreased menstrual volume, oligomenorrhea, secondary or primary amenorrhea account for about 15.1%.

2. Infertility: About 33.5% of women in their ovulatory period are infertile. When PRL is slightly elevated (<100-150ng/ml), it manifests as luteal insufficiency; when it is moderately elevated, it often manifests as infrequent menstruation and difficulty in conceiving; when PRL is extremely elevated, it manifests as amenorrhea and anovulatory infertility.

3. Decreased libido.

4. Twenty-seven point nine percent of women experience galactorrhea during the non-pregnancy and non-lactation period, and 75 point four percent experience both amenorrhea and galactorrhea. This condition needs to be differentiated from nipple discharge in patients with multiple papilloma in the milk ducts or breast cancer. Galactorrhea caused by prolonged stimulation of the breasts should also be ruled out.

5. Obesity.

6. Progressive bone pain, decreased bone density, and osteoporosis due to low estrogen levels.

7. Compression symptoms of pituitary tumors PRL adenoma is the most common cause of pathological hyperprolactinemia. Like other pituitary tumors, it causes related clinical symptoms due to the change in its position, especially pituitary macroadenomas (>10mm), including headache, decreased vision, visual field defects (due to compression of the optic chiasm, typical bilateral defects often occur) and other cranial nerve compression symptoms, epileptic seizures, cerebrospinal fluid rhinorrhea, etc. 15% to 20% of patients are at risk of spontaneous bleeding in pituitary adenomas, and 1/3 of them experience pituitary apoplexy, that is, headache, vomiting, decreased vision, eye muscle paralysis and other neurological symptoms.

The symptoms of hyperprolactinemia described above do not necessarily appear at the same time. If two or three symptoms appear, you should pay attention to it. It is likely that the disease is caused by high prolactin. You must receive relevant examinations in time for early detection and early treatment. Otherwise, the disease will seriously affect future fertility, cause irreversible consequences, and affect family harmony.