What are the common symptoms of hyperprolactinemia?

When understanding the symptoms of hyperprolactinemia, everyone must combine it with their own actual situation, because in addition to common characteristics, the symptoms of hyperprolactinemia also have individual reasons, so the analysis of the symptoms of hyperprolactinemia must be based on specific circumstances.

The most prominent manifestation of hyperprolactinemia is hypogonadism, which is caused by elevated PRL levels and is called hyperprolactinemic hypogonadism. Female patients may experience decreased libido and loss of sexual desire, which are relieved after treatment as PRL levels decrease. PRL mainly affects gonadal function at the hypothalamic level. PRL can stimulate the production of endogenous opioids, which can strongly inhibit the pulsatile release of GnRH, thereby reducing LH secretion.

The opioid receptor antagonist naloxone can normalize LH secretion and restore normal ovarian cycle in women with hyperprolactinemia, which can serve as evidence. If the course of the disease is long, the pituitary gland and gonads themselves will also be abnormal. Long-term hyperprolactinemia can reduce the response of the gonads to gonadotropins; GnRH deficiency can cause gonadotropin cells to atrophy and lead to reduced LH secretion. In women of childbearing age, hyperprolactinemic hypogonadism is mainly manifested as reduced menstruation or even amenorrhea, but it can also be manifested as menorrhagia or normal menstruation with infertility.

The above symptoms of hyperprolactinemia are relatively common. After understanding the symptoms of hyperprolactinemia, everyone is required to go to a regular hospital to treat this disease based on their own actual situation to ensure everyone's safety and health.