Hyperprolactinemia has three major symptoms

At present, the number of people suffering from hyperprolactinemia is gradually increasing. This disease has added a lot of troubles to the normal life and work of the majority of patients and friends, and has even more affected their physical and mental health. So what are the three major symptoms of hyperprolactinemia? Below, let's take a look at the three major symptoms of hyperprolactinemia.

Hyperprolactinemia refers to a series of pathological syndromes caused by multiple factors that cause the serum prolactin (PRL) concentration to exceed the upper limit of normal under non-physiological conditions.

Hyperprolactinemia is a hypothalamic-pituitary-gonadal axis dysfunction disease, the main symptoms of which are significantly reduced menstrual volume, oligomenorrhea or even amenorrhea, infertility, galactorrhea, menopausal symptoms, etc. This disease accounts for about 20% of endocrine-related infertility.

Clinical manifestations

1. Menstrual disorders

Primary amenorrhea 4%, secondary amenorrhea 89%, oligomenorrhea 7%, functional uterine bleeding and luteal dysfunction 23-77%.

2. Milk leakage

Typical HPRL manifestations include amenorrhea-galactorrhea syndrome, which occurs in 20.84% ​​of non-tumor types and 70.58% of tumor types, and simple galactorrhea in 63-83.55%. Galactorrhea is overt or occurs when the breast is squeezed, and is watery, serous, or milky. The breasts are mostly normal or with lobular hyperplasia or macromastia.

3. Infertility

70.71% are primary or secondary, caused by anovulation, corpus luteum deficiency or luteinized unruptured follicle syndrome (LUFS).

Through the above introduction, I believe everyone has a certain understanding of the three major symptoms of hyperprolactinemia.