Causes of hyperprolactinemia

Causes of hyperprolactinemia

What is the cause of hyperprolactinemia? It is necessary for everyone to understand this. Only by understanding the cause of hyperprolactinemia can we help everyone correctly diagnose and treat this disease. So what is the cause of hyperprolactinemia? The following is a professional answer given by experts.

Causes of Hyperprolactinemia:

① Physiological factors: pregnancy, postpartum and breastfeeding, eating, emotional stress and strenuous exercise can all cause hyperprolactinemia.

② Drug factors: Drug factors are the most common cause of hyperprolactinemia. According to reports, about 50% of women treated with antipsychotics have lactation, and the most likely to cause lactation is , about 75-80% of users may experience lactation and amenorrhea. Anesthetics such as morphine and heroin can also induce it. In addition, steroid hormones including synthetic estrogen and estrogen-progesterone combination drugs can all lead to hyperprolactinemia.

③Pathological factors: About 30% of patients with primary hypothyroidism have elevated prolactin levels and 2-5% have lactation. 60-70% of pituitary tumors are prolactinomas, and patients often have both lactation and amenorrhea. Prolactin adenoma is a common cause of pathological hyperprolactinemia. Chronic renal failure, local irritation such as thoracic surgery, trauma, herpes zoster or chronic breast irritation can cause hyperprolactinemia. Hypothalamic disorders such as hypothalamic tumors, degeneration, granulomas, vascular or infectious lesions can all cause hyperprolactinemia.

④ Functional or idiopathic factors: Idiopathic hyperprolactinemia is caused by abnormal regulation of pituitary lactocytes by the hypothalamus.

The above-mentioned causes of hyperprolactinemia are relatively common. After analyzing the causes of hyperprolactinemia, everyone is required to actively go to a regular hospital to treat this disease. Only in a regular hospital can everyone's safety and health be restored to the greatest extent.

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