Treatment for endometrial thickening

For some patients with moderate to severe endometrial thickness, doctors will recommend that they continue to take medication for a period of time after surgery to prevent the recurrence of endometrial thickness or to further shrink the residual lesions. The specific plans are as follows. Each plan has its pros and cons. Patients should weigh the pros and cons and choose the most appropriate medication based on their own condition, financial conditions, whether they want to get pregnant, and the doctor's advice.

1. Marvelon: Continuous or cyclical medication, a total of 3-6 cycles.

(1) Cyclic medication regimen: Take 1 tablet orally every night starting from the 5th day of menstruation for 21 consecutive days. After stopping the medication, start a new cycle of treatment from the 5th day of the next menstruation. If menstruation does not occur one week after stopping the medication, come to the hospital for examination.

(2) Continuous medication regimen: Take 1 tablet orally every night starting from the 5th day of the menstrual cycle for 6 consecutive months. Patients who take the medication continuously usually do not have menstruation.

Note: If a little vaginal bleeding occurs during medication, you can continue to take the medicine. If the amount of bleeding is heavy and similar to menstruation, stop taking the medicine and treat it as menstruation. Follow up in the outpatient clinic and recheck liver function after 2 months of medication.

2. High-efficiency progestins: medroxyprogesterone acetate, megestrol acetate, norethindrone, etc., taken orally once a night starting from the 5th day of the menstrual cycle, for 3-6 months.

Note: If a little vaginal bleeding occurs during medication, you can continue to take the medicine. If the amount of bleeding is similar to menstruation, increase the dosage of the medicine. Follow up in the outpatient clinic and recheck liver function after 2 months of medication.

3. Gestrinone: Take orally from the 2nd or 3rd day of the menstrual cycle, 2 times/week, 1 tablet each time, for 3-6 months.

Note: If a little vaginal bleeding occurs during medication, you can continue to take the medicine, but if the bleeding does not stop or the amount of bleeding is as much as menstruation, the dose of gestrinone needs to be adjusted. Follow-up in the outpatient clinic and recheck liver function after taking the medicine for 2 months.

4. GnRH-a: Subcutaneous or intramuscular injection, starting from the 1st to 3rd day of the menstrual cycle, once every 4 weeks, for a total of 3-6 times.

Note: A little vaginal bleeding during medication usually does not need to be treated. If menopausal symptoms occur after taking the medicine for a period of time, such as hot flashes, vaginal dryness, decreased libido, insomnia and depression, these symptoms are temporary and will disappear naturally after stopping the medication. If necessary, hormone supplements can be used to improve these symptoms.