Bacterial vaginosis is an inflammation of the vaginal mucosa and submucosal connective tissue, and is a common disease in gynecological clinics. It is extremely harmful to the human body. Here is a detailed introduction to what drugs can cure bacterial vaginosis. I hope the following content can help you. Anti-anaerobic drugs are mainly metronidazole and clindamycin. Metronidazole inhibits the growth of anaerobic bacteria without affecting the growth of lactobacilli. It is an ideal therapeutic drug, but has poor effect on mycoplasma. (1) Oral medication: The first choice is metronidazole 500 mg, twice a day, orally, for 7 days. Alternatively, metronidazole 2 g, taken all at once, is not as effective as taking it for 7 days. Alternatively, clindamycin 300 mg, twice a day, for 7 days. (2) Local drug treatment: 2. Apply clindamycin ointment vaginally, 5g each time, once a night, for 7 consecutive days, with a cure rate of 92-94%. Occasionally, there are symptoms of vaginal irritation, but there is no need to stop the drug; or 200mg of metronidazole effervescent tablets, once a night, for 7-14 days, or 5g of metronidazole gel vaginally, once a night, for a course of 5 days. The efficacy of local medication is similar to that of oral medication, with a cure rate of about 80%. (3) Treatment of sexual partners: Although this disease is related to multiple sexual partners, treating sexual partners does not improve the treatment effect or reduce the recurrence of the disease. Therefore, sexual partners do not need routine treatment, but sexual partners of patients with recurrent or refractory bacterial vaginosis should be treated. (4) Treatment of bacterial vaginosis during pregnancy: Since this disease is associated with adverse pregnancy outcomes, any symptomatic pregnant woman and asymptomatic high-risk pregnant woman (with a history of premature rupture of membranes and premature birth) should be screened and treated for bacterial vaginosis. Since this disease may be combined with subclinical infection of the upper reproductive tract during pregnancy, oral medication is often used. The treatment plan is metronidazole 200 mg, 3 to 4 times/d, for 7 consecutive days. Oral tinidazole treatment. The efficacy of BV is similar to that of metronidazole, with small toxic and side effects. The usage is 500 mg, twice a day, and 6 days is a course of treatment. Clindamycin 300 mg, orally, twice a day, for a course of 7 days. Metronidazole 500 mg can also be used, once a night, inserted deep into the vagina before going to bed, for 7 to 10 days. Due to experimental evidence that metronidazole has mutagenic effects on some bacteria and cell lines, and high-dose use in selective animal models can cause carcinogenic effects, metronidazole should be used with caution during pregnancy. However, decades of clinical practice have shown that there is no clear evidence that metronidazole is carcinogenic to humans. Vaginal administration of metronidazole has a preventive effect on bacterial vaginosis and adverse pregnancy outcomes in late pregnant women. |
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