How to differentiate functional uterine bleeding from systemic diseases?

Not long after Yuanyuan got married, her menstruation became irregular. It has been more than a year now. Every time, it is always wet and the amount of blood is also very large. Her husband is often troubled by this. Seeing his wife's illness, when can he hold his son? In fact, Yuanyuan is also annoyed, but she just feels a little embarrassed and doesn't want to go to the hospital. Seeing Yuanyuan's body getting weaker and weaker, her husband coaxed and deceived Yuanyuan to a small hospital. Yuanyuan was suspected of having a blood disease, which scared Yuanyuan. She didn't know how she got there. It was the husband who was calm. He took Yuanyuan to a large hospital the next day. After a careful examination by the doctor, it was confirmed to be functional uterine bleeding. Yuanyuan and her husband finally breathed a sigh of relief.

In fact, since functional uterine bleeding often leads to abnormal uterine bleeding, and some systemic diseases can also cause symptoms similar to functional uterine bleeding, they need to be differentiated from each other in diagnosis and treatment.

The most common blood disease is thrombocytopenic purpura, and others include aplastic anemia, leukemia, etc. The skin of patients with blood diseases often has bleeding diathesis. Physical examination may reveal petechiae, purpura, mucosal bleeding, etc. in addition to vaginal bleeding.

Endocrine diseases such as persistent anovulation caused by hyperthyroidism or hypothyroidism, adrenal cortical dysfunction and diabetes. Both hyperthyroidism and hypothyroidism can cause irregular menstruation. Patients often have varying degrees of abnormal vital signs such as tremors, changes in skin texture, weight changes, and may also have goiter.

Liver disease affects estrogen metabolism or the synthesis of coagulation factors. Patients with liver disease often suffer from coagulation disorders due to abnormal liver function. They may also have spider nevi, liver palms, splenomegaly, ascites, jaundice, flapping tremors, etc.

Others include renal failure after dialysis treatment; systemic lupus erythematosus, caused by damage to vascular function or the action of anticoagulant antibodies in the blood.