What causes vulvar leukoplakia?

Many women will have vulvar leukoplakia, which is also a gynecological disease. Facing the occurrence of vulvar leukoplakia, we cannot ignore it, but first we need to know the causes of vulvar leukoplakia so as to take preventive measures to avoid recurrence. So what are the causes of vulvar leukoplakia? Let's take a look at the causes of vulvar leukoplakia.

Causes of vulvar leukoplakia:

(I) Vulvar squamous epithelial hyperplasia: It is a vulvar disease with vulvar itching as the main symptom but unknown etiology. Although there is no direct cause of this disease, anatomical and physiological factors such as the long-term moisture of the local skin of the vulva and the stimulation of vaginal discharge may be related to its occurrence. This disease is more common in postmenopausal women, but it can also occur in reproductive age.

Vulvar itching is the main symptom of this disease, which is unbearable for patients. Since scratching the local area stimulates larger nerve fibers and inhibits the reflex of the itch nerve fibers, the patient's itching can be temporarily relieved, but scratching can cause further damage to the skin, thereby triggering new itching reactions and making the itching more severe, forming a vicious cycle.

The range of vulvar lesions varies, mainly involving the labia majora, interlabial groove, clitoral hood, posterior labial union, etc., and the length is symmetrical. When the early lesions are mild, the skin color is dark red or pink, and the hyperkeratotic area is white. Due to long-term scratching and friction, the skin thickens like leather, the pigment increases, the skin texture is obviously prominent, the skin ridges are raised, and there are many small polygonal flat papules, which are grouped into pieces and have lichenification. Therefore, this disease is also clinically called chronic simple lichen. Due to different degrees of local moisture, scratching and friction, and different reactions to local medications, the lesions in different parts of the patient are different in shape. In severe cases, scratching can cause epidermal scratches, cracks, and ulcers.

(ii) Vulvar lichen sclerosus: It is a skin disease characterized by atrophy and thinning of the vulva and perianal skin. Although the cause is unknown, there is a family history of this disease. Some scholars have also found that patients with this disease often have autoimmune diseases such as alopecia areata, vitiligo, hyperthyroidism or hypothyroidism, indicating that this disease is related to autoimmunity.

The above is an explanation of the causes of vulvar leukoplakia. Do you have a deeper understanding of the causes of vulvar leukoplakia? If you have symptoms of vulvar leukoplakia, please go to the hospital for examination and treatment in time, and the patient must maintain a good attitude and actively cooperate with the doctor's treatment. If you have any questions about vulvar leukoplakia, please consult our online experts to answer your questions.

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