What are the causes of uterine fibroids?

Since many patients with uterine fibroids do not know the causes of uterine fibroids, they are unprepared for this disease. Experts remind everyone that it is important to know the causes of uterine fibroids.

Uterine fibroids are a common disease in women, but the cause of uterine fibroids is still unclear. According to a large number of clinical observations and experimental results, fibroids are a type of tumor that depends on estrogen for growth. For example, they are common in women of childbearing age, 30 to 50 years old, especially in high estrogen environments, such as pregnancy, exogenous high estrogen, etc., and the growth is obvious, while the fibroids gradually shrink after menopause. Fibroid patients are often accompanied by ovarian congestion, swelling, and excessive growth of the endometrium, revealing that this is related to excessive estrogen stimulation. From the perspective of tissue development, uterine fibroid cells originate from smooth muscle cells of the uterine muscle and vascular wall, such as immature myoblasts, but the latter has not yet been clearly defined in histology. The occurrence of human uterine fibroids may come from the differentiation process of undifferentiated mesenchymal cells to smooth muscle cells. Multiple uterine fibroids may be due to the multifocal lurking of the origin cells in the myometrium. From this it seems that the cause of uterine fibroids is that after entering sexual maturity, the undifferentiated mesenchymal cells and mature smooth muscle cells remaining in the myometrium undergo a continuous proliferation, differentiation and hypertrophy process under the action of the estrogen and progesterone cycle, which is repeated over a long period of time and finally forms a tumor.

After reading the above information about the causes of uterine fibroids, I believe you have some understanding. If you still have related questions, you can click on our online experts for direct communication and the experts will give detailed answers.

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