What tests are needed for partial hydatidiform mole?

What tests are needed for partial hydatidiform mole?

1. B-ultrasound: Abdominal scans show that there may be dark areas of different sizes in the uterus, which are caused by blood accumulation in the uterine cavity. The fetus can also be found, that is, in addition to snowflake light films, there may also be images of the fetus and/or placenta. B-ultrasound diagnosis is non-invasive and has a high diagnosis rate. It is a powerful measure to diagnose hydatidiform mole.

2. hCG determination: hCG is used to diagnose and follow up hydatidiform mole. The amount of hCG is small at the beginning of normal pregnancy, reaches a peak at 8-10 weeks of pregnancy, and then gradually decreases. After 100 days of gestational age, the hCG level in twins and multiple pregnancies decreases significantly, and the hCG level is also higher than that in singleton pregnancies. In hydatidiform mole, the hCG level is much higher than normal and remains at a high level. The normal serum hCG level of non-pregnant women is <75mIU/ml, and β-hCG is <20mIU/ml. The median peak value of serum hCG in normal pregnant women is 100,000 mIU/ml and the highest value is 210,000 mIU/ml. The serum hCG value of patients with hydatidiform mole is much higher than 200,000 mIU/ml. Combined with clinical and B-ultrasound, a high value of a single hCG can confirm the diagnosis of hydatidiform mole. If hCG is quantitatively checked, if the hCG value is still very high after 14 weeks of pregnancy, the diagnosis can be clearer.

After 8 weeks of excluding hydatidiform mole, careful curettage confirms that there is no residual hydatidiform mole in the uterine cavity, no luteinized cyst, and serum hCG remains above 1000mIU/ml or rises. Later color enhancement confirms malignant changes. When the hCG value is below 1000mIU/ml and luteinized cysts exist, it is necessary to carefully check whether metastatic lesions exist, or if it may be caused by ovarian luteinized cysts, close follow-up should be performed. If the luteinized cyst disappears, hCG follow-up should continue according to benign hydatidiform mole.