Animal study: Celery extract turns obese cells into brown fat

The application scope of regenerative medicine stem cell technology is becoming increasingly wide. It can not only be applied to cancer, but now there are new discoveries in weight control! According to the latest announcement from the National Health and Family Planning Commission of the Ministry of Health and Welfare, the prevalence of overweight and obesity among adults in Taiwan has continued to rise in recent years, reaching an all-time high of 47.97% last year (109), which means that nearly 1 in every 2 adults is overweight!

Mice fed celery extract MTF-5 for 8 weeks had an average weight loss of 35%

Director Lin Xinrong of Hualien Tzu Chi Medical Center said that in the research on stem cells, MTF-5 was extracted from the natural plant celery and used on obese mice. Experiments have found that it can lower blood lipids and blood sugar, and can also turn obese cells into brown fat with high metabolism and the ability to consume heat energy. Animal experiments have found that when fattened mice were fed celery extract MTF-5 for eight consecutive weeks, their average weight decreased by 35%. This research was a joint collaboration between Hualien Tzu Chi Medical Center and Ivy Biotech.

Dean Lin Xinrong further stated that many natural foods contain MTF-5, and studies have found that celery has the highest content. However, if you want to lose weight by eating celery, you may have to eat at least 20 or 30 kilograms a day, and you may need to pay attention to the problem of overdose. This research has great potential for weight control and related metabolic symptoms. We are currently planning to publish the research results in international journals in the field of metabolism, and related patents are also being applied for.

iNKT cell amplification and culture technology has anti-cancer immunity and tumor suppression effects

In addition, Professor Kai-Hsin Lin, an authoritative physician in the Department of Pediatrics at the National Taiwan University Hospital and the head of the GTP Laboratory of Ivy Biotech, also published an iNKT cell amplification and culture technology that has anti-cancer immunity and tumor suppression effects. In the future, it can not only be extended to treat autoimmune diseases such as systemic lupus erythematosus and arthritis, and metabolic syndrome such as atherosclerosis and non-alcoholic fatty liver disease, but can even effectively treat cancer. It is the most anticipated new immunotherapy today.

According to the latest statistics on causes of death in Taiwan released by the National Health Administration of the Ministry of Health and Welfare, cancer has been ranked first among the top ten causes of death for 38 consecutive years. Faced with the threat of cancer, compared with traditional treatments, such as chemotherapy, which destroys cells throughout the body and has strong side effects; targeted therapy can specifically attack cancer cells, but is more likely to develop drug resistance. In recent years, a new treatment option has emerged - immunotherapy. Immunotherapy can activate the patient's own immune system through stem cells to attack cancer cells. It is not limited by the frequent medication required in the past and has low side effects. It can be said to be a major breakthrough in cancer treatment in recent years.

Sources of stem cells include umbilical cord blood, spinal cord and peripheral blood. Among them, peripheral blood stem cells have lower risks in collection and faster patient recovery. Ivy Biotechnology controls the quality of cell storage through a sterile GTP laboratory. In the future, it is expected to be used to treat many blood malignancy-related diseases, such as leukemia, lymphoma, multiple myeloma, chronic ischemic stroke, diabetic complications, etc.

iNKT cell amplification and culture technology will also be used in allogeneic transplantation of peripheral blood stem cells in the future

iNKT cells combine the advantages of T cells and NK killer cells, have both immune regulation and toxicity, and have anti-cancer immunity and tumor suppression effects. The iNKT cell number amplification and culture technology will also be used in allogeneic transplantation of peripheral blood stem cells in the future to solve the problem of insufficient peripheral blood stem cell providers, which is truly a great boon for patients.