If a woman has habitual miscarriage, she needs to undergo endocrine diagnosis and anatomical examinations, as well as immune examinations, pathogen infection examinations, and prethrombotic state diagnosis. It should be noted that these examinations are very important, and it is recommended that women follow the doctor's instructions and undergo strict examinations. During pregnancy, there are always many unexpected events, such as the influence of some human factors of the pregnant woman herself; some external environmental factors may cause the fetus to have habitual miscarriage. So, if habitual miscarriage occurs, what should be checked? Let's find out below! 1. Endocrine diagnosis <br/>Endocrine abnormalities that lead to miscarriage include gynecological endocrine abnormalities and internal medicine endocrine abnormalities. Gynecological endocrine abnormalities include common corpus luteum dysfunction, hyperprolactinemia, polycystic ovary syndrome, etc. Gynecological endocrine abnormalities should be checked by basal body temperature measurement (BBT), endometrial biopsy, hormone measurement, serum prolactin (PRL) measurement, etc.; internal medicine endocrine abnormalities are mainly diabetes and thyroid dysfunction, and related diseases and hormones should also be checked. 2. Anatomical factors examination <br/>The anatomical factors that cause habitual abortion mainly include the following aspects: cervical insufficiency, uterine malformation (such as uterine septum, unicornuate uterus, bicornuate uterus, saddle uterus, etc.), uterine fibroids or adenomyomas, intrauterine adhesions, etc. Diagnosis mainly relies on ultrasound, intrauterine iodized oil angiography, hysteroscopy, laparoscopy, cervical dilator and other examinations. 3. Immune examination <br/>Immune abortion includes alloimmune disorder and autoimmune abnormality. The screening of alloimmune disorder requires blocking antibody, couple HLA matching and other tests. Currently, blocking antibody is the most common and practical test. If the blocking antibody is negative, it means that the mother cannot produce "blocking antibodies" that protect the embryo. The embryo will be attacked by the mother's immune cells and prone to developmental arrest. Autoimmune abnormality requires the examination of antibodies in the mother's body, such as antiphospholipid antibodies, antisperm antibodies, antiprogesterone antibodies, antiestrogen antibodies, etc. Doctors must find out which antibodies have a greater impact on habitual abortion. 4. Examination of pathogen infection <br/>Although infection factors are not the direct cause of habitual abortion, the positive rate of various infections in the reproductive tract of patients with habitual abortion is very high, reaching about 50%. Therefore, before getting pregnant again, the reproductive tract must be examined for pathogens to understand whether there is microbial infection and give corresponding treatment. 5. Diagnosis of prethrombotic state <br/>The diagnosis of prethrombotic state requires examination of the patient's coagulation function. The coagulation function test is quite complicated, and the tests that can be done currently are only the tip of the iceberg of the overall picture of coagulation function. In addition, the cost of coagulation function tests is relatively high, so the examination items currently carried out in hospitals are relatively limited. |