Is premature ovarian failure hereditary?

Is premature ovarian failure hereditary? This is a question that many female friends are concerned about. Hereditary diseases often make people unable to sleep or eat, because it not only endangers the patient's own health, but also has a certain impact on the next generation. So, is premature ovarian failure hereditary? The following is a detailed introduction for everyone.

There are many factors that cause premature ovarian failure clinically, and the specific pathogenesis is still unclear. However, most experts believe that it is related to genetic factors, immune factors, iatrogenic factors, artificial abortion, pituitary dysfunction, and severe ovarian damage caused by childhood viral mumps. Therefore, premature ovarian failure is hereditary to a certain extent.

Through careful analysis of family history, the incidence of familial premature ovarian failure has been reported to be 4% to 31% in different populations, indicating that genetic factors play a major role in premature ovarian failure. X chromosome abnormalities have long been recognized as the main cause of premature ovarian failure. With the progress of molecular biology, researchers have also discovered more and more candidate genes related to premature ovarian failure on autosomes.

If there are female relatives in the family who have menopause before the age of 40, have chromosomal abnormalities, or have undergone pelvic surgery, the risk of premature ovarian failure is higher than that of the general population. In addition, negative psychological emotions will reduce the secretion of immune active substances, and strong emotional fluctuations or huge mental stimulation will affect the central nervous system, leading to irregular menstruation and premature ovarian failure.

In fact, in daily life, female friends can prevent themselves from suffering from premature ovarian failure through some preventive measures. The human central nervous system and endocrine system are interconnected and influence each other. When people are in a good mood, all indicators of the body are in a balanced and coordinated state, the secretion of immune active substances is vigorous, and the body's resistance is strong.

On the contrary, bad mood can affect the body's immunity and lead to a variety of diseases. Women should be good at regulating emotions, correctly dealing with psychological conflicts, maintaining a good attitude, and learning to vent negative emotions in a healthy way. Cheer up, try to keep a good mood, and prevent premature ovarian failure.