What is the main cause of congenital absence of vagina?

Congenital absence of vagina is a congenital malformation, most commonly seen in patients with Rokitansky-Kustner-Hauser syndrome, who have normal female chromosome karyotype, normal systemic growth and development of female secondary sexual characteristics, normal vulva, vaginal absence, uterine development (only remnants of two horns), small fallopian tubes, and normal ovarian development and function. So, what is the main cause of congenital absence of vagina?

What is the main cause of congenital absence of vagina?

Generally speaking, congenital absence of vagina occurs when the mother uses anti-cancer drugs containing male hormones in the early stages of pregnancy, which stops the reaction and causes female developmental abnormalities, resulting in congenital absence of vagina. It may also be because the patient's constitution is insensitive to androgens, or there are chromosomal abnormalities, all of which may cause the disease. Some women are infected with certain viruses or toxoplasmosis in the early stages of pregnancy, which may cause symptoms of congenital absence of vagina in the baby girl, so women should pay enough attention when they are pregnant.

Usually, congenital absence of vagina is caused by the stagnation of development of the tail end of the mesonephric duct during embryonic development and its failure to extend downward. It may be accompanied by incomplete uterine development or uterine underdevelopment. Some patients may also have uterine developmental abnormalities. If the uterus is abnormal, women will experience symptoms of primary amenorrhea after entering puberty, or have a small or deformed uterus. If the uterus develops normally, it may be accompanied by periodic abdominal pain, intrauterine blood, uterine enlargement, sexual life disorders, etc. Women should not have too much psychological burden about these situations and should face the disease correctly.

No matter what disease we have, we must find it early, prevent it early, and treat it early, so that the disease will not spread and become uncontrollable. Especially for those patients with more serious diseases, remember to go to a professional Shi Nu Hospital for treatment.