A Guide for Pregnant Patients with Hyperprolactinemia

Prolactin actually refers to a hormone secreted by the pituitary gland. This hormone can stimulate the mammary glands and secrete follicle-stimulating hormone and luteinizing hormone. If prolactin is too high or too low, it will affect the secretion of appropriate hormones, follicle-stimulating hormone and luteinizing hormone, and will also affect ovulation function. So hyperprolactinemia will affect pregnancy

The main symptoms of hyperprolactinemia are amenorrhea, galactorrhea, anovulation and infertility. Therefore, patients with hyperprolactinemia will be affected in having babies. After prolactin is elevated, it will directly affect the function of the hypothalamus, pituitary gland and ovarian axis, which will reduce serum estrogen and cause abnormal ovarian ovulation. Therefore, follicles do not develop, ovulation does not occur and corpus luteum function is insufficient, resulting in infertility. For such patients, ovulation induction treatment can generally be used, mainly bromocriptine, combined with other ovulation induction drugs to promote ovulation and achieve pregnancy.

If prolactin (PRL) and thyroid function are not ideal, those who are anxious to get pregnant should have monthly checkups so that the doctor can find the appropriate dosage as soon as possible. For those who are not anxious to get pregnant, a checkup once every 1-2 months is fine. If prolactin (PRL) and thyroid function are already ideal, a checkup can be done once every 1-3 months.