The dangers of surgery for hyperprolactinemia

If hyperprolactinemia is pathological, it is a disease and needs treatment. For this disease, the treatment measures are different at different stages. The following is an introduction to the surgical treatment methods of this disease, I hope it will be helpful to everyone.

Introduction to surgical treatment methods:

It is suitable for patients with giant adenomas that present intracranial compression symptoms, who are ineffective with bromocriptine treatment, giant adenomas, and serotonin-induced cell tumors that secrete multiple pituitary hormones. The current transsphenoidal microsurgery is safe, convenient, and easy to perform, and its efficacy is similar to that of bromocriptine therapy. The combination of bromocriptine before and after surgery can improve the efficacy. The disadvantages of surgery are that pituitary tumors have no obvious capsule and unclear boundaries, and it is not easy to be thorough or damaged during surgery, which can cause cerebrospinal fluid nasal fistula and postoperative hypopituitarism. It is worth noting that although preoperative bromocriptine treatment can shrink the tumor, it can cause tumor fibrosis, sclerosis, and adhesion of surrounding tissues, which is not conducive to surgical separation and resection. Therefore, if surgery is determined, medication can be temporarily stopped before surgery, and medication or radiotherapy can be supplemented after surgery.

When does hyperprolactinemia require surgical treatment?

When pituitary tumors produce obvious compression symptoms and neurological symptoms or drug treatment is ineffective, surgical removal of the tumor should be considered. Taking bromocriptine for a short period of time before surgery can reduce the size of the tumor and reduce intraoperative bleeding, which helps to improve the efficacy. Transsellar microsurgery is now more commonly used.

What are the risks of surgical treatment for hyperprolactinemia?

The disadvantages of surgery are: if the pituitary tumor has no obvious capsule and unclear boundaries, it is difficult to completely remove it. It may cause cerebrospinal fluid rhinorrhea and secondary pituitary function