The dangers of hyperprolactinemia cannot be ignored

Experts say that hyperprolactinemia refers to a syndrome caused by internal and external environmental factors, characterized by elevated PRL (≥25ng/ml), amenorrhea, galactorrhea, anovulation and infertility. The main manifestations of hyperprolactinemia are menstrual disorders, galactorrhea and infertility. The hazards of hyperprolactinemia that cannot be ignored are introduced in detail below.

Hyperprolactinemia is characterized by:

1. Galactorrhea. Typical HPRL manifestation is amenorrhea. Galactorrhea syndrome occurs in 20.84% ​​of non-tumor type and 70.58% of tumor type. Simple galactorrhea occurs in 63-83.55% of cases. Galactorrhea is overt or appears as watery, serous or milky fluid when the breast is squeezed. Most breasts are normal or accompanied by lobular hyperplasia or macromastia.

2. Infertility: 70.71% of infertility is either primary or secondary and is caused by anovulatory corpus luteum deficiency or luteinized unruptured follicle syndrome.

3. Menstrual disorders: primary amenorrhea 4%, secondary amenorrhea 89%, oligomenorrhea 7%, functional uterine bleeding, and luteal dysfunction 23-77%.

What are the dangers of hyperprolactinemia?

Experts say that the hazards of hyperprolactinemia are mainly the following:

(I) Changes in vision and visual field: When pituitary tumors involve the optic chiasm, vision loss, headache, dizziness, hemianopsia and blindness, as well as damage to cranial nerves II, III and IV, fundus edema and exudation may occur.

(ii) Low estrogen reaction: seen in people with long-term amenorrhea, such as hot flashes, palpitations, spontaneous sweating, vaginal dryness, dyspareunia, decreased libido, etc.

(III) Acromegaly: It occurs in PRL-GH adenoma with elevated GH.

(IV) Hyperandrogenism: moderate obesity, seborrheic dermatitis, acne and hirsutism.

(V) Diabetes mellitus and abnormal glucose tolerance test.

(VI) Myxedema: seen in combination with hypothyroidism.

[Warm reminder] The above is the expert's introduction to "What are the hazards of hyperprolactinemia?" I hope it will be helpful to you.