There are several ways to check for cervical warts

Cervical warts have caused trouble to many patients, not only causing physical harm to them, but also causing great psychological damage. Therefore, when we suspect that we have cervical warts, we must go to the hospital for examination and treatment as soon as possible. Now, let’s take a look with the editor at what examinations we should do.

The first type, histochemical examination:

Take a small amount of lesion tissue from patients with cervical condyloma and make a smear, then stain it with specific anti-human papillomavirus antibodies. If there is a viral antigen in the lesion, the antigen and antibody will bind. In the peroxidase antiperoxidase (PAP) method, the nucleus can be stained red. This method is highly specific and rapid, which is helpful for diagnosing cervical condyloma.

Second, immunohistological examination:

The peroxidase antiperoxidase method (PAP) is commonly used to show viral proteins in condylomata, to prove the presence of viral antigens in warts. When HPV protein is positive, a weak red positive reaction may appear in the superficial epithelial cells of patients with cervical condylomata.

The third type, acetic acid white test:

Apply 3-5% acetic acid to the wart for 2-5 minutes, and the lesion will turn white and slightly raised. It may take 15 minutes for anal cervical wart lesions. The principle of this test is the result of protein coagulation and acid whitening. The keratin produced by infected cells of cervical warts is different from that produced by normal uninfected epithelial cells. Only the former can be decolorized by acetic acid. The acetic acid whitening test is very sensitive in detecting cervical warts.

Fourth, pathological examination:

The main manifestations of cervical condyloma are parakeratosis, hypertrophy of the spinous layer, papilloma-like hyperplasia, thickening and elongation of the epidermal protrusions, and the degree of hyperplasia may be similar to pseudoepithelioma. The thorn cells and basal cells have a considerable number of nuclear divisions, which are quite similar to AI-G changes. However, the cells are arranged regularly, and the boundary between the hyperplastic epithelium and the dermis is clear. The characteristic of cervical condyloma is that the cells in the upper part of the granular layer and the thorn layer have obvious vacuoles. This kind of vacuolated cell is larger than normal, with light cytoplasm and a large, round, deeply basophilic nucleus in the center. Usually there is dermal edema, capillary dilation, and dense chronic inflammatory infiltration around.