Can Chlamydia Cervicitis Be Cured?

Chlamydia and mycoplasma are very small microorganisms that cause human infection. They have several main characteristics. One is that the initial symptoms of infection are not very obvious. Often when we find it, it has been a long time and has infected other tissues or organs. So the initial symptoms are not obvious. The second characteristic is that the harm caused by chlamydia and mycoplasma is relatively large, especially to the reproductive system. Third, the treatment of chlamydia and mycoplasma is relatively difficult. Mycoplasma and chlamydia are two pathogens. Mycoplasma is relatively small, and chlamydia is relatively large. They mainly cause urinary and reproductive system infections in the human body. Chlamydia can also cause trachoma and pneumonia. These two pathogens can exist in the human body at the same time.

Infecting the human urinary and reproductive system, these two pathogens can exist at the same time or separately. At present, chlamydia and mycoplasma are still classified as one category in clinical practice. Male chlamydial urethritis, also known as non-gonococcal urethritis (NGU). It is a non-acute suppurative inflammatory lesion of the urethral mucosa caused by chlamydial infection. The incubation period of this disease is longer than that of gonorrhea, about 1-3 weeks or several months. The main manifestations are discomfort, stinging and burning sensation in the urethra, accompanied by varying degrees of frequent urination, urgency and pain when urinating. The pain when urinating is milder than that of gonorrhea. The urethral opening is slightly swollen and has serous or mucopurulent secretions, which are thin and small in quantity. If you do not urinate for a long time or before the first urination in the morning, you can see that the urethral opening secretions contaminate the underwear, and you can see that there is a "mud mouth" phenomenon in the urethral opening; when the secretion is small, a small amount of mucus will flow out of the urethra when you squeeze the urethra in the morning. Female chlamydia infection is not limited to the urethra, but can affect the entire urogenital organs. The incubation period of mycoplasma infection is 1-3 weeks. The typical acute symptoms are similar to other non-gonococcal genital urinary system infections, manifested as urethral stinging, varying degrees of urgency and frequency of urination, and stinging when urinating, especially when the urine is more concentrated. The urethral opening is slightly swollen, the secretion is thin, small in quantity, and serous or purulent. You often need to squeeze the urethra hard to see the secretion overflow. There is often a small amount of mucous secretion or only a crust membrane seals the urethral opening in the morning. Chlamydia cervicitis or dirty crotch Chlamydia and mycoplasma are microorganisms between bacteria and viruses.

Chlamydia trachomatis is a type of microorganism that parasitizes in cells and is about 250-450nm in size. Chlamydia is not heat-resistant and quickly loses its infectivity at room temperature. It can be killed in 30 minutes by heating it to 50°C. However, Chlamydia is cold-resistant and can survive for several years at -70°C. Mycoplasma is the smallest prokaryotic organism that can live independently. Mycoplasma that can cause human diseases is called human mycoplasma. Mycoplasma is 200nm in size and has no hard cell wall structure, so it is polymorphic in morphology. Humans are the natural hosts of at least 11 types of mycoplasmas, and 5 types of mycoplasmas (Mycoplasma pneumoniae, Mycoplasma hominis, Ureaplasma urealyticum, Mycoplasma genitalium and Mycoplasma crypticum) are pathogenic to humans. Human genital mycoplasmosis is caused by Mycoplasma hominis, Mycoplasma genitalium and Ureaplasma urealyticum. Mycoplasma is less resistant to the external environment than bacteria. It is killed in 15 minutes at 45℃. It is sensitive to soap, alcohol, bile salts, tetracycline, erythromycin, kanamycin, etc. Treatment of genital mycoplasma infection For the treatment of genital mycoplasma infection, the pros and cons must be weighed and it must be done carefully, not too aggressive. The treatment of the spouse or sexual partner of the infected person should also be cautious. The key is to target other sexually transmitted pathogens that may co-exist. There are many mycoplasma infected people who have been treated with antibiotics for a long time, but the mycoplasma test is still positive, and many new discomforts have also appeared. The reasons are extremely complicated, and mycoplasma resistance, detection errors or reagent failures, double infection (those who use antibiotics for a long time are prone to fungal and other insensitive bacterial infections), psychological factors, etc. may all be involved.

Generally speaking, drugs that are effective against chlamydia infection are also effective against mycoplasma infection. If necessary, for chlamydial cervicitis, tetracyclines (commonly used are tetracycline, doxycycline, minocycline), macrolides (commonly used are erythromycin, erythromycin ethylsuccinate, roxithromycin, azithromycin) and quinolones (commonly used are ofloxacin, levofloxacin) and spectinomycin, clindamycin, clarithromycin, etc. can be used to treat genital mycoplasma infection, and the course of treatment is 1 to 2 weeks. Erythromycin is ineffective against mycoplasma hominis, and clindamycin is ineffective against ureaplasma urealyticum. For female pelvic inflammatory disease, its multifactorial nature should be considered, and treatment should include antibiotics against gonococci, Chlamydia trachomatis, mycoplasma hominis and anaerobic bacteria. Foreign countries recommend the combined treatment of cefoxitin + doxycycline or clarithromycin + gentamicin. For prostatitis that may be caused by mycoplasma infection, minocycline should be used for treatment, because minocycline can pass through the prostate capsule and reach the drug concentration required to kill mycoplasma in the prostate. It is worth mentioning that the cause of prostatitis is complex, and the effect of antibiotic treatment is not necessarily good. Comprehensive treatment is required, and it is best to follow the advice of urology experts for treatment.

In recent years, the problem of mycoplasma resistance to antibiotics has attracted much attention. The abuse of antibiotics in chlamydial cervicitis may be an important factor leading to mycoplasma resistance. It has been reported that 10% to 20.6% of Ureaplasma urealyticum strains are resistant to tetracycline, 8% to 27.5% to doxycycline, and 10% to 52.4% to erythromycin. Nearly 20% of Ureaplasma urealyticum and Mycoplasma hominis strains are resistant to ofloxacin. In addition, mycoplasmas resistant to roxithromycin and azithromycin have also been reported. Since mycoplasma resistance to antibiotics has an increasing trend, it should be taken into consideration when using drugs clinically. Some experts advocate that in the treatment of mycoplasma infection, in order to reduce or prevent the emergence of resistant strains, it is advisable to use 2 to 3 different types of antibiotics for combined treatment. At the same time, Chinese medicine can also be given as an auxiliary treatment, but no specific Chinese medicine for the treatment of mycoplasma has been found. Chlamydia cervicitis In short, genital mycoplasma infection is a controversial issue in the medical community. Whether mycoplasma is the cause of diseases such as urethritis, prostatitis and pelvic inflammatory disease has not yet been confirmed. Genital mycoplasma infection exists not only in patients with sexually transmitted diseases and people at high risk of sexually transmitted diseases, but also in healthy people (including infants and young children). Chlamydia cervicitis Therefore, genital mycoplasma is not necessarily a sexually transmitted disease, and not all of them need to be treated. The treatment of genital mycoplasma infection depends on the specific situation, and it should not be impatient or hasty.