Ectopic pregnancy refers to the implantation of the fertilized egg outside the uterine cavity. The following types of women are prone to ectopic pregnancy: Those with a history of ectopic pregnancy According to surveys, among women who have had an ectopic pregnancy, 10% to 15% will have another ectopic pregnancy, 50% may be infertile, and the rest may have a normal intrauterine pregnancy. Clinically, it has been found that women with a history of ectopic pregnancy generally have another ectopic pregnancy in the contralateral fallopian tube. Patients with chronic salpingitis Under normal circumstances, the fallopian tube can transport the fertilized egg to the uterine cavity through the swaying of cilia and the peristalsis of the fallopian tube smooth muscle. Women with chronic salpingitis have difficulty in getting the fertilized egg to the uterine cavity due to inflammation and pathological changes. Those with hypoplastic or malformed fallopian tubes The lesions such as hypoplastic fallopian tube muscle layer and lack of cilia in the endometrium reduce the function of the fallopian tube in transporting fertilized eggs. The malformation of the fallopian tube also makes it difficult for the fertilized egg to reach the uterine cavity smoothly. Patients with tubal ligation and recanalization Regardless of whether it is natural recanalization or surgical recanalization, the fallopian tube is not as unobstructed as before, and the recanalized area is relatively narrow, so the fertilized egg can easily be trapped in the narrow area and settle down. Patients with endometriosis The endometrium in the interstitial part of the fallopian tube narrows or blocks the lumen, making it difficult for the fertilized egg to pass through. In addition, when the fertilized egg comes into contact with the ectopic endometrium, the syncytial cells differentiate from the cytotrophoblast cells and secrete a mucosal dissolving protease to erode the ectopic membrane, forming a gap for the fertilized egg to implant and develop, thus leading to an ectopic pregnancy in the interstitial part of the fallopian tube. Patients with pelvic tumors Due to the squeezing and traction of the tumor, the position of the uterus or fallopian tube will move, causing structural abnormalities, which will hinder the fertilized egg from reaching the uterine cavity. |
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