Hyperplastic vulvar leukoplakia is a type of vulvar leukoplakia, which has the common characteristics of vulvar leukoplakia, namely, thickening of the epidermis, loss of pigmentation in the basal layer of the epidermis, and reduction of blood vessels in the superficial dermis, causing the vulvar skin or mucous membrane to lose color or become white. The pathological changes of this type are manifested as hyperkeratosis or parakeratosis of the epidermis, thickening of the prickle cell layer, downward extension of the epithelial feet, and varying degrees of lymphocyte and plasma cell infiltration in the superficial dermis. Hyperplastic vulvar leukoplakia is common in women aged 30 to 60, and is rarely seen in infants or young girls. The disease is characterized by severe vulvar itching symptoms. Most patients scratch their vulva due to unbearable itching. Scratching or rubbing may be accompanied by obvious pain. The local skin is obviously raised and thickened, with rough wrinkles. Local epidermal keratinization may also occur with scaling or eczema-like changes. Gynecological examination can find that the patient's genitals are light red or brown, the epidermis is rough, there are scratches, and sometimes chapped. The bilateral labia minora, labia minora, clitoris, etc. are whitish or diffusely white and thickened like leather. Hyperplastic vulvar leukoplakia rarely causes vulvar atrophy or adhesion, so most patients have no sexual intercourse disorders. According to the differences in symptoms and pain suffered by patients, hyperplastic vulvar leukoplakia can be divided into three stages, namely stage I hyperplastic vulvar leukoplakia, stage II hyperplastic vulvar leukoplakia, and stage III hyperplastic vulvar leukoplakia. Although the disease brings great pain to patients, they can recover quickly after active treatment. |
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