Progesterone withdrawal test to exclude various types of amenorrhea

Progesterone withdrawal test to exclude various types of amenorrhea

Ms. Liu, 26 years old, unmarried, has been menopausal for 5 years. She usually has heavy menstruation and thin menstruation. She stopped menstruating 5 years ago due to a change in her living environment. After menopause, she gained weight significantly, had high blood pressure, diabetes, memory loss, and hair loss. Last year, she was examined in the Endocrinology Department of Capital Hospital and was initially diagnosed with adrenal and pituitary lesions. In March and April this year, she received pituitary radiotherapy in the hospital. During this period of menopause, Ms. Liu often felt dizzy, tinnitus, palpitations, chest tightness, abdominal distension, and back and leg pain.

To treat amenorrhea, doctors prescribed a progestin withdrawal trial.

Progesterone injection, 20 mg per day, intramuscular injection, for 5 consecutive days. After stopping the medication, Ms. Liu had no withdrawal bleeding, a negative reaction, and the doctor diagnosed her with II degree amenorrhea. Next, an estrogen-progesterone sequential test was performed.

Estrogen can be taken orally with estradiol valerate 2 mg or conjugated estrogen (Premarin) 1.25 mg daily for 21 consecutive days. After 10 days, medroxyprogesterone 10 mg daily can be added orally. Withdrawal bleeding after discontinuation of the medication is positive, indicating that the endometrium is functioning normally. Excluding uterine amenorrhea, the cause of amenorrhea is low estrogen levels in the body, and the cause should be further investigated.

<<:  What tests should be done if menstruation is not coming?

>>:  Gua Sha is economical and effective in treating amenorrhea

Recommend

Complications of bacterial vaginosis Various treatments for vaginitis

Vaginitis is one of the diseases that troubles ma...

What are the harms of menopause to patients?

Among gynecological diseases, menopause does not ...

Abnormal leucorrhea, blood, and no menstruation

Abnormal vaginal discharge with blood and missed ...

What is the cause of Trichomonas vaginitis?

Trichomonas vaginitis is a common gynecological d...

Yogurt, cereal, toast...Why do you feel hungrier the more you eat these foods?

I obviously eat a lot, but I always feel not full...

What are the common symptoms of acute pelvic inflammatory disease?

Everyone knows that there are types of pelvic inf...

Is there any treatment for ovulation bleeding?

In the middle of the menstrual cycle, that is, du...

What to do if uterine prolapse occurs

What should I do if I have uterine prolapse? Firs...

What if the menstrual flow is too little?

What if my menstrual flow is too little? Insuffic...

How much does it cost to test for cervical warts?

Cervical warts are the most serious disease. It i...

What causes cervical hypertrophy in women?

Cervical hypertrophy in women may be caused by ce...

External treatments that effectively relieve dysmenorrhea

In addition to taking medication to relieve pain,...