Can patients with hydatidiform mole still have a normal pregnancy?

Patients with hydatidiform mole can become pregnant normally after standardized treatment. Hydatidiform mole is a gestational trophoblastic disease, which is divided into two types: complete and partial. Its treatment is mainly uterine curettage. After surgery, hCG levels need to be closely followed up to ensure that pregnancy is considered only after it returns to normal.

1. The causes of hydatidiform mole include genetic factors, environmental factors and maternal factors. Among genetic factors, complete hydatidiform mole is usually formed by the combination of an empty egg and a haploid sperm, while partial hydatidiform mole may be caused by fertilization of two sperms. Environmental factors such as advanced maternal age, malnutrition, and vitamin A deficiency may increase the risk of disease. Maternal factors such as a history of hydatidiform mole and a history of miscarriage may also lead to hydatidiform mole.

2. The treatment of hydatidiform mole is centered on curettage, and hCG levels need to be closely monitored after surgery. Curettage removes abnormal tissue in the uterine cavity through negative pressure suction or curettage. The hCG level is monitored weekly after surgery until it is negative for three consecutive times. If the hCG level continues to rise or is abnormal, it is necessary to be alert to the possibility of malignant transformation, and chemotherapy or hysterectomy should be performed if necessary.

3. Precautions for patients with hydatidiform mole who become pregnant again include strict contraception, regular follow-up and pregnancy monitoring. Strict contraception should be used for 6-12 months after treatment to ensure that hCG levels return to normal. A comprehensive pre-pregnancy check-up is required before becoming pregnant again, and ultrasound monitoring should be strengthened during pregnancy to detect abnormal pregnancy early. Maintaining good living habits and avoiding contact with harmful substances can reduce the risk of another hydatidiform mole.

After standardized treatment and follow-up, the success rate of re-pregnancy for patients with hydatidiform mole is comparable to that of the normal population. The key is to strictly follow postoperative management and pregnancy monitoring to ensure the safety of mother and baby. For women with a history of hydatidiform mole, pre-pregnancy consultation and pregnancy management should be carried out under the guidance of professional doctors to reduce the risk of recurrence of hydatidiform mole.