What are the causes of vulvar leukoplakia

What are the causes of vulvar leukoplakia?

The main causes of vulvar leukoplakia are as follows:

1. Vulvar infection and inflammatory stimulation: This is the main cause of vulvar leukoplakia, accounting for about 50%. There are many factors that cause vulvar infection and inflammatory stimulation, such as poor hygiene habits, wearing chemical fiber underwear, unclean sanitary products, bathing in the bathroom, swimming in the bathroom, etc., leading to vaginal inflammation. If not treated in time, the inflammatory secretion will penetrate into the perineum. Long-term infection and stimulation will damage the skin and mucous membranes, causing redness, swelling, ulcers and degeneration, and gradually develop into vulvar leukoplakia.

2. Endocrine disorders: Endocrine diseases are caused by pathological changes in endocrine glands and tissues, or by endocrine disorders caused by genetics, enzyme defects, and immune function. The determination of tritium H3 thymidine shows that there is a protein hormone in the dermis that can inhibit the division and growth of epidermal cells and only acts on the local tissue-specific epidermis, called inhibitor. It causes local connective tissue hyperplasia and stimulates epidermal metabolic imbalance, leading to vulvar leukoplakia.

3. Genetic factors: about 10 patients with vulvar leukoplakia - 30%. It is caused by heredity. The hereditary leukoplakia is mainly atrophic, and the patients are mainly young children. Clinically, patients under 15 years old should first pay attention to genetic factors and ask their parents whether there are patients with vulvar leukoplakia in their family.

4. Other diseases: such as diabetes, vitiligo, vulvar eczema, vulvar itching, etc., such as drug abuse and improper treatment, may also cause or aggravate the formation and development of white spots.