Is hydatidiform mole contagious?

Hydatidiform mole is a common gynecological disease, and it is extremely harmful. It not only endangers the health and life of patients with hydatidiform mole, but also poses a certain threat to the life safety of patients with hydatidiform mole. Therefore, it is very necessary to do a good job in the prevention of hydatidiform mole. So is there any infectious factor in hydatidiform mole?

Experts remind that hydatidiform mole is not contagious and the true cause of hydatidiform mole is unknown. Case-control studies have found that the occurrence of hydatidiform mole is related to nutritional status, socioeconomic status and age. Age is a significant related factor in etiology. The incidence of hydatidiform mole in women over 40 years old is 10 times higher than that in young women. Women under 60 years old are also a high-risk factor for complete hydatidiform mole. Women in these two age groups are prone to fertilization defects. Partial hydatidiform mole has nothing to do with the age of the pregnant woman.

Through cytogenetics combined with pathological studies, it is proved that the two types of hydatidiform mole have their own genetic characteristics. The chromosome genome of complete hydatidiform mole is of paternal origin, that is, the egg develops after combining with the sperm pronucleus when the ovum pronucleus is missing or inactivated. The chromosome karyotype is diploid, of which 90% is 46,XX, and is formed by the fertilization of an empty egg (an egg without genetic material) and a haploid sperm (23,X), which is restored to diploid (46,XX) through self-replication and then grows and develops. This is called empty egg fertilization. A few of them have a karyotype of 46,XY, which is caused by two sperms with different sex chromosomes (23,X and 23,Y) fertilizing the empty egg at the same time, which is called disperm fertilization. The karyotype of partial hydatidiform mole is often triploid.

It can be seen that the reasons why the fetus of a pregnant woman becomes a hydatidiform mole are not only closely related to the nutrition of the pregnant woman, but also have an inseparable relationship with the chromosomes of the parents. There are large genetic factors. If parents find that they are pregnant with a hydatidiform mole, they must seek treatment in time to prevent the disease from worsening and becoming a malignant tumor.