What are the causes of congenital absence of vagina?

What is the cause of congenital absence of vagina? This is of great concern, because for us, it is generally recognized that only causal treatment of any disease can achieve ideal results. So what is the cause of congenital absence of vagina? The following is a detailed analysis.

Patients with congenital absence of vagina have normal external genitalia, with or without a hymen, and a shallow depression or short lower vagina. Most patients with congenital anterior vagina have only a completely closed vaginal vestibule mucosa at the normal vaginal opening, with no vaginal traces. Some patients also have a shallow depression in the vaginal vestibule, and some have a blind vagina shorter than 3 cm. It is often accompanied by no deformity, and only slightly thickened strip-like tissue can be seen in the normal uterus, located in the middle of the broad ligament.

Causes of congenital absence of vagina:

1. Chromosome abnormality;

2. Infection with certain viruses or toxoplasma in early pregnancy;

3. The mother used male hormone anticancer drugs such as thalidomide in early pregnancy;

4. Androgen insensitivity syndrome.

In the past, the most common method used was the patient's own free medium-thickness skin graft. However, after surgery, a hard vaginal mold needs to be used for a long time to expand the artificial vagina to prevent the artificial cavity covered by the grafted skin from contracting, which increases the patient's pain and brings great inconvenience to the worker and life. Moreover, the characteristics of skin and mucosal tissues are too different, and they do not meet physiological requirements, which is their biggest disadvantage. Vaginoplasty using labia skin flaps destroys the normal vulva shape and is often rejected by patients. Reconstruction using sigmoid colon or ileum segments increases the complexity of the operation.

The causes of congenital absence of vagina are very complicated, so everyone must correctly understand the cause of the disease based on their own actual situation. Only by correctly understanding the cause and treating the cause can the best treatment effect be achieved and unnecessary harm of the disease be avoided.