What are the causes of congenital absence of vagina?

I believe that everyone is not particularly familiar with the symptoms of congenital absence of vagina in female friends. The appearance of this disease is not particularly common in life, but the harm it brings to female friends is very great. So what is the cause of congenital absence of vagina? Let us learn about it together:

This disease is caused by the obstruction of the embryo during development by internal or external factors, or by abnormal development of the paramesonephric duct due to gene mutation (may have a family history). The most common patients with Rokitansky-Kustner-Hauser syndrome are characterized by normal female chromosome karyotype, normal systemic growth and development of female secondary sexual characteristics, normal vulva, vaginal absence, uterine development (only remnants of two horns), small fallopian tubes, and normal ovarian development and function. Testicular feminization (androgen insensitivity syndrome) patients are relatively rare. Very few are true hermaphroditism or gonadal dysgenesis.

The above is an introduction to some relevant content about the cause of congenital absence of vagina. We hope that these contents can provide some useful help to friends in need and remind friends that the harm caused by this disease is very great, so we must actively face and treat the occurrence of this disease.