Symptoms of hyperprolactinemia

Hyperprolactinemia, if it is pathological, will have other clinical manifestations in addition to the physiological increase in milk. To understand the disease, you have to understand its symptoms. The following is an introduction to the symptoms of the disease, I hope you can read it carefully.

Symptoms of hyperprolactinemia

(1) Menstrual disorders: primary amenorrhea accounts for 4%, secondary amenorrhea accounts for 90%, oligomenorrhea and oligomenorrhea account for 7%, and dysfunctional bleeding and luteal insufficiency account for 23% to 77%.

(2) Galactorrhea The incidence of typical amenorrhea-galactorrhea syndrome is 20% in non-tumor hyperprolactinemia, 70% in tumor-type, and 65% in simple galactorrhea. Galactorrhea is overt or occurs when the breast is squeezed and is watery, serous, or milky. The breasts are usually normal.

(3) The incidence of infertility is 70%, which can be primary or secondary infertility and is related to anovulation, luteal insufficiency or luteinized unruptured follicle syndrome (LUFS).

(4) Hypoestrogenemia and hyperandrogenism: Decreased estrogen levels cause hot flashes, palpitations, spontaneous sweating, vaginal dryness, dyspareunia, decreased libido, etc. Increased androgen levels cause moderate obesity, seborrheic dermatitis, acne, and hirsutism.

(5) Changes in vision and visual field: When pituitary tumors involve the optic chiasm, they can cause decreased vision, headaches, dizziness, hemianopsia and blindness, as well as functional impairment of cranial nerves II, III and IV, and fundus edema and exudation.

(6) Acromegaly: seen in PRL-GH adenoma, myxedema seen in combined hypothyroidism, some patients have type 2 diabetes and osteoporosis.